Results 111 to 120 of about 93,092 (385)

From Constantinople to the South Caucasus: Deciphering the urban landscape in John Dos Passos’s travel memoir “Orient Express”

open access: yesUrbis et Orbis: Mikroistoriâ i Semiotika Goroda
This article examines a highly-regarded but little-studied work of the major American novelist John Dos Passos, the travel memoir Orient Express (1927), the account of a 1922 journey from Constantinople, through the South Caucasus and through Iran and ...
Albert Makaryan   +1 more
doaj   +1 more source

m6A‐Mediated TMCO3 Promotes Hepatocellular Carcinoma Progression by Facilitating the Membrane Translocation and Activation of AKT

open access: yesAdvanced Science, EarlyView.
TMCO3 as a downstream target of ALKBH5 is found, which regulates its expression in an m6A‐dependent manner, and then a new phosphorylation site on TMCO3 is identified and determines the specific mechanism of TMCO3 with AKT. Moreover, the combined treatment of targeting the TMCO3 and inhibition of AKT in mice models with HCC achieves great results ...
Xinxin Li   +8 more
wiley   +1 more source

Natural history of liver disease in a large international cohort of children with Alagille syndrome: Results from the GALA study

open access: yesHepatology, EarlyView., 2022
Natural history of liver disease in a large international cohort of children with Alagille syndrome: Results from the GALA study. Abstract Background and Aims Alagille syndrome (ALGS) is a multisystem disorder, characterized by cholestasis. Existing outcome data are largely derived from tertiary centers, and real‐world data are lacking.
Shannon M. Vandriel   +93 more
wiley   +1 more source

Synthesis of Pt Carbon Aerogel Electrocatalysts with Multiscale Porosity Derived from Cellulose and Chitosan Biopolymer Aerogels via Supercritical Deposition for Hydrogen Evolution Reaction

open access: yesAdvanced Energy and Sustainability Research, EarlyView.
The synthesis of platinumcarbon aerogel electrocatalysts with multiscale porosity derived from biopolymer aerogels via supercritical deposition is presented. The electrocatalysts demonstrate similar overpotentials to commercial alternatives with significantly higher platinum loadings, while exhibiting superior stability due to enhanced porosity ...
Ala Alsuhile   +6 more
wiley   +1 more source

c‐Rel–dependent Chk2 signaling regulates the DNA damage response limiting hepatocarcinogenesis

open access: yesHepatology, EarlyView., 2022
In response to genotoxic injury, c‐Rel upregulates ATM‐Chk2‐p53 pathway DNA damage proteins to limiting hepatocarcinogenesis. Abstract Background and Aims Hepatocellular carcinoma (HCC) is a leading cause of cancer‐related death. The NF‐κB transcription factor family subunit c‐Rel is typically protumorigenic; however, it has recently been reported as a
Jack Leslie   +17 more
wiley   +1 more source

All roads lead to (New) Rome: Byzantine astronomy and geography in a rapidly changing world [PDF]

open access: yesarXiv
During the first few centuries CE, the centre of the known world gradually shifted from Alexandria to Constantinople. Combined with a societal shift from pagan beliefs to Christian doctrines, Antiquity gave way to the Byzantine era. While Western Europe entered an extended period of intellectual decline, Constantinople developed into a rich cultural ...
arxiv  

Large Language Model‐Based Chatbots in Higher Education

open access: yesAdvanced Intelligent Systems, Volume 7, Issue 3, March 2025.
The use of large language models (LLMs) in higher education can facilitate personalized learning experiences, advance asynchronized learning, and support instructors, students, and researchers across diverse fields. The development of regulations and guidelines that address ethical and legal issues is essential to ensure safe and responsible adaptation
Defne Yigci   +4 more
wiley   +1 more source

CD11b+CD43hiLy6Clo splenocyte‐derived macrophages exacerbate liver fibrosis via spleen–liver axis

open access: yesHepatology, EarlyView., 2022
A population of splenic monocytes migrate into the liver and shift to macrophages, which account for the exacerbation of liver fibrosis. Abstract Background and Aims Monocyte‐derived macrophages (MoMFs), a dominant population of hepatic macrophages under inflammation, play a crucial role in liver fibrosis progression.
Shaoying Zhang   +18 more
wiley   +1 more source

Cloud‐Based Control System with Sensing and Actuating Textile‐Based IoT Gloves for Telerehabilitation Applications

open access: yesAdvanced Intelligent Systems, EarlyView.
Using cloud computing technology, a telerehabilitation application allows patients to perform exercises remotely. Sensor data from a textile‐based IoT glove is processed in the cloud and transmitted as exercise commands to an actuating T‐IoT glove worn by patients.
Kadir Ozlem   +5 more
wiley   +1 more source

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