Results 111 to 120 of about 161,884 (244)

Patient‐Reported Outcomes with Selpercatinib Among Patients with RET Fusion–Positive Non‐Small Cell Lung Cancer in the Phase I/II LIBRETTO‐001 Trial

The Oncologist, EarlyView., 2021
Abstract Background LIBRETTO‐001 is an ongoing, global, open‐label, phase I/II study of selpercatinib in patients with advanced or metastatic solid tumors. We report interim patient‐reported outcomes in patients with RET fusion–positive non‐small cell lung cancer (NSCLC).
Anna Minchom, Aaron C. Tan, Erminia Massarelli, Vivek Subbiah, Valentina Boni, Bruce Robinson, Lori J. Wirth, Lisa M. Hess, Min‐Hua Jen, Jennifer Kherani, Elizabeth Olek, Caroline E. McCoach   +11 more
wiley   +1 more source

Factors related to loss to follow‐up and low compliance in Helicobacter pylori‐infected children: The EuroPedHp Registry

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Factors related to loss to follow‐up and low compliance in Helicobacter pylori‐infected children. Abstract Objectives Monitoring for Helicobacter pylori (H. pylori)‐eradication is important, since symptom improvement does not indicate treatment success. Using EuroPedHp Registry data, we investigated characteristics of children missing monitoring visits
Thu Giang Le Thi, Kallirroi Kotilea, José Cabral, Michal Kori, Maria Luz Cilleruelo, Marta Tavares, Josefa Barrio, Vaidotas Urbonas, Matjaž Homan, Zrinjka Misak, Nicolas Kalach, Pedro Urruzuno, Martina Klemenak, Andreas Krahl, Andrea Chiaro, Josef Sykora, Meltem Korkut Ugras, Jan de Laffolie, Erasmo Miele, Alexandra Papadopoulou, Sibylle Koletzko, for the Helicobacter pylori & other Gastritis Special Interest Group of ESPGHAN, Thu Giang Le Thi, Kallirroi Kotilea, José Cabral, Michal Kori, Maria Luz Cilleruelo, Marta Tavares, Josefa Barrio, Vaidotas Urbonas, Matjaž Homan, Zrinjka Misak, Nicolas Kalach, Pedro Urruzuno, Martina Klemenak, Andreas Krahl, Andrea Chiaro, Josef Sykora, Meltem Korkut Ugras, Jan de Laffolie, Erasmo Miele, Alexandra Papadopoulou, Sibylle Koletzko   +42 more
wiley   +1 more source

Patient‐Reported Outcomes with Selpercatinib Treatment Among Patients with RET‐Mutant Medullary Thyroid Cancer in the Phase I/II LIBRETTO‐001 Trial

The Oncologist, EarlyView., 2021
Abstract Background Medullary thyroid cancer (MTC) standard of care includes multikinase inhibitors (MKIs), which can exacerbate disease‐related diarrhea, primarily because of non‐RET kinase inhibition. We report diarrhea and other patient‐reported outcomes (PROs) with selpercatinib, a highly selective RET inhibitor, among patients with RET‐mutant MTC ...
Lori J. Wirth, Bruce Robinson, Valentina Boni, Daniel S.W. Tan, Caroline McCoach, Erminia Massarelli, Lisa M. Hess, Min‐Hua Jen, Jennifer Kherani, Elizabeth Olek, Vivek Subbiah   +10 more
wiley   +1 more source

Liver stiffness in patients with Shwachman‐Diamond syndrome

JPGN Reports, EarlyView.
Abstract Objective This case series aims to describe whether transient elastography (TE) as a marker of liver stiffness is associated with clinically important liver disease in children and young adults with Shwachman‐Diamond Syndrome (SDS). Methods All patients ≤25 years of age with genetically confirmed SDS seen in the Pediatric Gastroenterology ...
Sabina Sabharwal, Amit Grover, Paul Mitchell, Jessica Serino‐Cipoletta, Akiko Shimamura, Rima Fawaz   +5 more
wiley   +1 more source

Menetrier's: A pediatric chronic state of disease with a possible heritable form

JPGN Reports, EarlyView.
Abstract Menetrier's disease (MD) is a rare, typically transient, hypertrophic gastropathy with under 1000 adult cases and 50 pediatric cases known worldwide. Pediatric cases most often present with an infectious etiology. We present a case of a teenage male expressing a chronic state of disease without infectious origin.
MariaElena Terzis, Anna Furr, Julia Fritz   +2 more
wiley   +1 more source

Ileal bile acid transporter inhibitors for chronic constipation in the elderly. [PDF]

World J Gastrointest Pharmacol Ther
Aneesh PSR, Vaithiyam V, Reddy RT, Dalal A, Sachdeva S.   +4 more
europepmc   +1 more source

Observational study of metastatic vulvar Crohn's disease in the pediatric population

JPGN Reports, EarlyView.
Abstract Objective Metastatic vulvar Crohn's disease (MVCD) is a rare cutaneous manifestation of Crohn's disease (CD), especially in pediatric patients. The objective of this study is to assess presentation, diagnosis, and treatment for pediatric MVCD in the largest cohort reported. Methods This is a retrospective review of pediatric patients with MVCD
Deborah Winograd, Afua Addo, Taryn Wassmer, Jennifer Hellmann, Daniel Mallon, Kalyani Marathe, Christine Pennesi   +6 more
wiley   +1 more source

Collagenous gastritis: A cause of anemia and gastric nodularity in the pediatric population

JPGN Reports, EarlyView.
Abstract We present a case series of seven pediatric patients with collagenous gastritis (CG) with the aim of contributing data to existing literature about this rare disease to assist in the understanding and management of these patients. Gross nodularity seen on esophagogastroduodenoscopy and increased subepithelial collagen on biopsy were noted in ...
Megan Emiliani, Dyer Heintz, Marisa Izaguirre   +2 more
wiley   +1 more source

Outcomes Following Constipation Treatments Between Parkinson's Disease and Non-Parkinson's Disease Patients Evaluated by the Constipation Scoring System. [PDF]

Parkinsons Dis
Methawasin K, Krittayasingh A, Khuancharee K, Chonmaitree P, Wongwandee M.   +4 more
europepmc   +1 more source

Toilet training and bowel habits in children up to 4 years: Insights from a population‐based prospective cohort study

JPGN Reports, EarlyView.
Abstract Objectives Recognizing bowel dysfunction and toilet training issues can be challenging due to conflicting information about what is normal. This study aims to provide an overview of toilet training practices and bowel habits in healthy children up to 4 years. Methods This study among 6850 parent–child pairs was part of the Generation R Study—a
Demi Huijgen, Tarik Karramass, Hendt P. Versteegh, Vincent W. V. Jaddoe, Cornelius E. J. Sloots   +4 more
wiley   +1 more source