Results 111 to 120 of about 337,411 (342)

Obstructive Uropathy in a Child with Severe Chronic Constipation

Proceedings of Singapore Healthcare, 2012
Urinary symptoms are well-described in children with chronic constipation which include enuresis, urgency and recurrent urinary infections. Renal tract obstruction is a rare complication of severe chronic constipation. We describe a case of a 10-year-old
Veena Logarajah MBBS, MRCPCH, Kong Boo Phua MBBS, M Med (Paeds), FRACP, FAMS, FRCPE, FRCPCH, Te Lu Yap MBBS, FRCS (Glasgow), Christina Ong MBBS, FRCPCH   +3 more
doaj   +1 more source

Translating Research to Practice for Children With Autism Spectrum Disorder: Part 2: Behavior Management in Home and Health Care Settings [PDF]

, 2016
Introduction Managing home and health care for children with autism spectrum disorder can be challenging because of the range of symptoms and behaviors exhibited. Method This article presents an overview of the emerging science related to the methods to
Bultas, Margaret W., Burkett, Karen, Johnson, Norah L., PhD, RN, CPNP, Reinhold, Judy   +3 more
core   +1 more source

Negative association between body roundness index and constipation: insights from NHANES

Journal of Health, Population and Nutrition
Backgrounds The relationship between body roundness index (BRI), a metric that distinguishes heterogeneity in fat distribution, and constipation is unclear.
Lingting Chen, Huirong Xiao, Xuchao Yu, Bingbin Huang, Sirong Guo, Ting Yuan, Siyang Deng   +6 more
doaj   +1 more source

Quality of life and chronic pain four years after gastrointestinal surgery [PDF]

, 2006
PURPOSE: Little is known about the prevalence of chronic postsurgical pain after gastrointestinal surgery. This study was designed to assess the prevalence of chronic pain and quality of life in a cohort of patients who underwent surgery for benign and ...
Bruce, Julie, Krukowski, Zygmunt H.
core   +1 more source

Relative Bioavailability, Food Effect, and Bioequivalence Studies to Assess a New Zanubrutinib 160‐mg Tablet: Results From 2 Phase 1 Studies in Healthy Volunteers

Clinical Pharmacology in Drug Development, EarlyView.
Abstract Zanubrutinib is a next‐generation Bruton tyrosine kinase inhibitor approved for treating B‐cell malignancies. Two phase 1 studies evaluated a new 160‐mg zanubrutinib tablet versus 80‐mg capsules. In study BGB‐3111‐115 (n = 43), a randomized 3‐period crossover trial, relative bioavailability and food effects were assessed.
Bilal Tariq, Chester Lin, Vaibhav Mundra, Yang Gao, Dan Zhang, Ying C. Ou   +5 more
wiley   +1 more source

The effect of mother’s and infant nutrition on functional constipation in children between 1-4 months

Trends in Pediatrics
Objective: Constipation is the infrequent and painful passage of hardened stools, occurring less than three times a week, often accompanied by excessive straining and discomfort.
Gülberat Totur, Maşallah Baran
doaj   +1 more source

Comparison of three with six regions of interest analyses in patients with idiopathic constipation undertaking colon transit scintigraphy using 67Ga-citrate [PDF]

, 2013
OBJECTIVE AND INTRODUCTION: Preparation of data from 6 geometric regions of interest in the colon is time consuming, and can become impractical in the environment of busy Nuclear Medicine Departments.
Asli, I.N., Assadi, M., Ehsani, M.J., Javadi, H., Semnani, S., Tabib, S.M.   +5 more
core  

Effects of Single-Dose Prucalopride on Intestinal Hypomotility in Horses: Preliminary Observations [PDF]

, 2017
Abnormalities of gastrointestinal motility are often a challenge in horses; however, the use of prokinetic drugs in such conditions must be firmly established yet.
Bassotti, G., Faillace, Vanessa, Fettucciari, K, Fratini, Margherita, Laus, Fulvio, Paggi, Emanuele, Spaterna, Andrea, Tesei, Beniamino   +7 more
core   +2 more sources

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Multiple Ascending Doses and Dose Titration of Bexicaserin in Healthy Participants in a Randomized, Double‐Blind, Placebo‐Controlled Study

Clinical Pharmacology in Drug Development, EarlyView.
Abstract Bexicaserin (LP352) is a selective superagonist of the 5‐hydroxytryptamine 2C (5‐HT2C) receptor currently in development for the treatment of seizures that arise from developmental and epileptic encephalopathies. This phase 1, double‐blind, placebo‐controlled multiple ascending dose (MAD) study assessed the safety, tolerability, and ...
Jonathan Williams, Rosa Chan, Chad Orevillo, Gale O'Connell, Dewey McLin, Shikha Polega, Nuggehally R. Srinivas, Randall Kaye   +7 more
wiley   +1 more source

Frequency patterns of core constipation symptoms among the Asian adults: a systematic review

BMC Gastroenterology, 2017
Background In clinical practice, assessment of constipation depends on reliability, consistency and frequency of several commonly reported or core symptoms.
Abdul Wahab Patimah, Yeong Yeh Lee, Mohd Yusoff Dariah   +2 more
doaj   +1 more source