Results 131 to 140 of about 389,522 (398)
International Forum of Allergy &Rhinology, EarlyView.ABSTRACT Objective There is limited consensus on endoscopic skull base surgery (ESBS) reconstruction principles. This study aims to generate comprehensive themes regarding ESBS reconstruction by pooling the experiences of ESBS experts, with comparison to a literature review of current published evidence.
Edward C. Kuan +77 more
wiley +1 more source
Predictors of slow colonic transit in children
, 2014 PURPOSE: Slow transit constipation (STC) and functional fecal retention (FFR) are two forms of severe intractable constipation in childhood diagnosed by nuclear transit studies (NTS).
Croaker, Geoffrey David Hain +2 more
core +1 more source
The Guanylate Cyclase C-cGMP Signaling Axis Opposes Intestinal Epithelial Injury and Neoplasia. [PDF]
, 2018 Guanylate cyclase C (GUCY2C) is a transmembrane receptor expressed on the luminal aspect of the intestinal epithelium. Its ligands include bacterial heat-stable enterotoxins responsible for traveler\u27s diarrhea, the endogenous peptide hormones ...
Rappaport, Jeffrey A., Waldman, Scott A.
core +2 more sources
Animal Models and Experimental Medicine, EarlyView.In a study combining network pharmacological analysis and experimental verification, yunweiling has been shown improve functional constipation by inhibiting the PI3K‐Akt‐p53 signaling pathway and reducing the expression of TP53. Abstract Background This study investigated the impacts and mechanisms of yunweiling in the management of Functional ...
Peng Zhang +6 more
wiley +1 more source
Food intolerance and chronic constipation: manometry and histology study. [PDF]
, 2006 BACKGROUND: Chronic constipation in children can be caused by cows' milk intolerance (CMI), but its pathogenesis is unknown. AIMS: To evaluate the histology and manometry pattern in patients with food intolerance-related constipation.
BONVENTRE, Sebastiano +8 more
core +1 more source
Exenatide Once Weekly in the Treatment of Patients with Multiple System Atrophy
Annals of Neurology, EarlyView.Objective Exenatide, a glucagon‐like peptide‐1 (GLP‐1) receptor agonist, has neuroprotective effects in preclinical models of multiple system atrophy (MSA). We investigated these effects in a proof‐of‐concept clinical trial. Methods In this single‐center, randomized, open label trial, participants with MSA were randomly assigned (1:1) to receive ...
Nirosen Vijiaratnam +29 more
wiley +1 more source
Heart Rate Profiles During Exercise and Incident Parkinson's Disease
Annals of Neurology, EarlyView.Objective To determine whether established heart rate parameters of exercise, related to cardiac autonomic function, are associated with incident Parkinson's disease, independent of both clinical and autonomic prodromal features. Methods A study of UK Biobank participants who performed a standardized bicycle exercise test (2009–2013), followed until ...
Stefan van Duijvenboden +13 more
wiley +1 more source
Managing constipation in adults with co-morbidities [PDF]
, 2016 Constipation can be described in a number of ways but in general it is related to straining, reduced frequency of defecation and/or a sensation of incomplete bowel emptying.
Gardiner, Anji, Hilton, Andrea
core +1 more source
CONSTIPATION IN INFANTS. [PDF]
JAMA: The Journal of the American Medical Association, 1904 Complete digestion embraces a three-fold function—viz., conversion, absorption and evacuation. There is a conversion and an absorption of the nutrient element of food, and following these is an evacuation of the refuse. The successful performance of these several divisions of the digestive function is dependent on each other, on the character of food ...
openaire +2 more sources