Results 161 to 170 of about 337,411 (342)

Efficacy, safety, and relapse outcomes of MAPK inhibitors in pediatric Langerhans cell histiocytosis: A real‐world study

International Journal of Cancer, EarlyView.
What's new? Mitogen‐activated protein kinase (MAPK) inhibitors are promising treatments for pediatric Langerhans cell histiocytosis (LCH), a rare heterogeneous neoplasm that often affects multiple organ systems. Which MAPK inhibitors are most effective against LCH remains uncertain.
Xue Tang, Jing‐jing Sun, Zhi Wan, Xiao‐yu Jing, Xia Guo, Ju Gao   +5 more
wiley   +1 more source

Leveraging artificial intelligence for evidence‐based recommendations in uterine fibroid therapy: Addressing the unmet need in German healthcare—A clinical trial

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To evaluate the potential of an artificial intelligence (AI)‐driven large language model, ChatGPT 4.0, to provide personalized, evidence‐based treatment recommendations for uterine fibroids. Methods ChatGPT 4.0 was trained using evidence‐based data from Uptodate and German medical literature.
Iason Psilopatis, Laura Lotz, Nadezda Sipulina, Felix Heindl, Georgia Levidou, Julius Emons   +5 more
wiley   +1 more source

Long‐term results of the Musset surgical technique in the treatment of recto‐vaginal fistulas

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective Recto‐vaginal fistulas (RVF) are a rare pathology, mostly affecting developing countries. They are mainly obstetrical (88% of cases) and have an incidence of 0.5%. Musset's surgical technique in the management of RVF has been the subject of few studies and there is little data in the literature concerning the evaluation of its long ...
Joy Bloomfield, Bassam Haddad, Geoffroy Canlorbe, Cyril Touboul, Edouard Lecarpentier, Yohann Dabi   +5 more
wiley   +1 more source

Pediatric Functional Constipation: A New Challenge

Advanced Gut & Microbiome Research
Functional constipation is a common gastrointestinal disorder worldwide in children, adolescents, and adults. Functional constipation is persistent, difficult, and infrequent hard stooling with incomplete rectal emptying that does not have an ...
Samina Khan Bashir, Muhammad Bashir Khan
doaj   +1 more source

The Relationship Between Depression and Constipation: Results From a Large Cross-sectional Study in Adults [PDF]

, 2021
Peyman Adibi, Maryam Abdoli, Hamed Daghaghzadeh, Ammar Hassanzadeh Keshteli, Hamid Afshar, Hamidreza Roohafza, Ahmad Esmaillzadeh, Awat Feizi   +7 more
openalex   +1 more source

Robot‐assisted resection of diaphragmatic and hepatorenal recess peritoneal endometriosis: Two cases and a narrative review

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract In this report, we describe two cases of diaphragmatic endometriosis with concurrent hepatorenal recess peritoneal involvement managed using robotic‐assisted laparoscopic surgery with the da Vinci Xi platform. In both patients, diaphragmatic implants and hepatorenal recess peritoneal lesions were excised en bloc, followed by resection of ...
Xiaoming Guan, Qiannan Yang, Daniel Y. Lovell, Chunhua Zhang   +3 more
wiley   +1 more source

Multistrain Probiotics Plus Vitamin D Improve Gut Barrier Function and Gut Microbiota Composition in Irritable Bowel Syndrome Without Constipation: Results from a Double-Blind, Randomized, Placebo-Controlled Trial [PDF]

Lucrezia Laterza, Cesare Cremon, Gaetano Coppola, Carlo Romano Settanni, Rossella Maresca, Martina Strazzeri, Eleonora Durini, Valentina Petito, Franco Scaldaferri, Giorgio Gargari, Diego Mora, Ebrahim Yazdi, Chiara Marangelo, Gianluca Ianiro, Lorenza Putignani, Maria Raffaella Barbaro, Giovanni Marasco, Giovanni Barbara, Antonio Gasbarrini   +18 more
openalex   +1 more source

Utility of high-resolution anorectal manometry and wireless motility capsule in the evaluation of patients with Parkinson's disease and chronic constipation [PDF]

, 2016
Andrew Su, Rita Gandhy, Carrolee Barlow, George Triadafilopoulos   +3 more
openalex   +1 more source

Clinical trial of safety and antitumor activity of farletuzumab ecteribulin in patients with platinum‐resistant ovarian cancer: Phase I expansion results

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective In the dose‐escalation part of Study 101, which included multiple tumor types, objective responses were observed in 10 of 22 patients across multiple dose levels of farletuzumab ecteribulin (FZEC). We explored the safety/antitumor activity of FZEC in patients with platinum‐resistant ovarian cancer (PROC) from the Study 101 expansion ...
Kan Yonemori, Mayu Yunokawa, Koji Matsumoto, Kazuhiro Takehara, Kosei Hasegawa, Yasuyuki Hirashima, Hidenori Kato, Hiroki Ikezawa, Yohei Otake, Wataru Yusa, Takuma Miura, Shin Nishio   +11 more
wiley   +1 more source

Identification of a De Novo MAGEL2 Pathogenic Variant in Schaaf–Yang Syndrome and the Importance of Paternal Allele Confirmation

Journal of Clinical Laboratory Analysis, EarlyView.
This study reports a de novo MAGEL2 pathogenic variant in a patient with Schaaf–Yang syndrome, confirmed through methylation‐sensitive analysis. Combining genomic sequencing with methylation assays helps accurately determine the parental origin of MAGEL2 mutations.
Youn‐Ji Hong, Misun Yang, Hyeon Jeong Kwon, Jooyoung Cha, Ja‐Hyun Jang, Sung Eun Wang, Eun Sun Lee, Mi‐Ae Jang   +7 more
wiley   +1 more source