Results 171 to 180 of about 389,522 (398)

Symptom Onset in Classic Rett Syndrome: Analysis of Initial Clinical Severity Scale Entries

open access: yesAnnals of the Child Neurology Society, EarlyView.
ABSTRACT Objective We aim to assess the clinical features of Rett syndrome (RTT) at registration into the National Institutes of Health–sponsored natural history study (NHS) using the Clinical Severity Scale (CSS). Introduction The CSS was established in 2000 to assess characteristics of individuals with RTT and related disorders.
Alan K. Percy   +4 more
wiley   +1 more source

Safety and Efficacy of the NMDA‐2b‐Selective Negative Allosteric Modulator BI 1569912: A Phase Ib Randomized Trial in Major Depressive Disorder

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Selective N‐methyl‐D‐aspartate receptor subunit 2b negative allosteric modulators (NR2B NAMs) are being explored as potential new treatment options for major depressive disorder (MDD). This Phase Ib, randomized, double‐blind, placebo‐controlled, parallel‐group trial was conducted in adults (N = 59) with moderate‐to‐severe MDD and insufficient response ...
Roger S. McIntyre   +9 more
wiley   +1 more source

Traitements anciens et nouveaux de la constipation [PDF]

open access: bronze, 1959
Jeanette M. Johnstone   +23 more
openalex   +1 more source

Evaluation of Constipation and Treatment of Abdominal Constipation

open access: yes, 2016
Constipation is a prevalent condition that can have significant effects on quality of life. Initial treatment should include behavioral modification and fiber supplementation or laxatives. In patients that require further intervention, testing modalities are available to aid in differentiating between constipation subtypes.
Muneera R. Kapadia, Madhulika K. Varma
openaire   +2 more sources

Epidemiology and Burden of Chronic Constipation

open access: yesCanadian Journal of Gastroenterology, 2011
Chronic constipation is an important component of clinical gastroenterology practice worldwide. Based on the definition, either self-reported or using Rome criteria, chronic constipation can affect from 2% to 27% of the population.
Maria Ines Pinto Sanchez, Premysl Bercik
doaj   +1 more source

Translating Research to Practice for Children With Autism Spectrum Disorder: Part 2: Behavior Management in Home and Health Care Settings [PDF]

open access: yes, 2016
Introduction Managing home and health care for children with autism spectrum disorder can be challenging because of the range of symptoms and behaviors exhibited. Method This article presents an overview of the emerging science related to the methods to
Bultas, Margaret W.   +3 more
core   +1 more source

Intestinal microbiome alterations in pediatric epilepsy: Implications for seizures and therapeutic approaches

open access: yesEpilepsia Open, EarlyView.
Abstract The intestinal microbiome plays a pivotal role in maintaining host health through its involvement in gastrointestinal, immune, and central nervous system (CNS) functions. Recent evidence underscores the bidirectional communication between the microbiota, the gut, and the brain and the impact of this axis on neurological diseases, including ...
Teresa Ravizza   +4 more
wiley   +1 more source

Elucidating the Potential of Dietary Hemp Seed on Gut Health: Recent Advances and Future Perspectives

open access: yesFood Chemistry International, EarlyView.
Hemp seed has been shown to improve gut health by enhancing intestinal barrier function, increasing the expression of tight junction proteins, reducing pro‐inflammatory cytokines, modulating gut microbiota composition, and influencing the production of short‐chain fatty acids, which contribute to overall gut homeostasis.
Dekun Cheng   +3 more
wiley   +1 more source

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