Abstract Background The lived experience of Parkinson's disease (PD) includes motor and non‐motor symptoms. There is a need to capture the earliest patient experiences in a sensitive and reliable manner for the successful development of interventions that may delay clinical progression in PD.
Joseph Saade+3 more
wiley +1 more source
<i>Weizmannia Coagulans</i> BC99 Prevents Loperamide-Induced Functional Constipation in Mice Through Increased Intestinal Peristalsis and Modulation of Gut Microbiota Dysbiosis. [PDF]
Li C+7 more
europepmc +1 more source
Abstract Background Dopaminergic neuron depletion in the substantia nigra (SN) and the pathological aggregation of α‐synuclein are the neuropathological hallmarks of Parkinson's disease (PD). Objectives This study aimed to investigate the association between the polygenic risk score for PD (PD‐PRS) and transcranial sonography (TCS)‐measured SN ...
Mart Kals+11 more
wiley +1 more source
Maternal smoking around birth is associated with an increased risk of offspring constipation: Evidence from a Mendelian randomization study. [PDF]
Shen Y+5 more
europepmc +1 more source
The Gut‐Brain Axis in Parkinson disease: Emerging Concepts and Therapeutic Implications
Abstract Background The gut‐brain axis, i.e. the bidirectional communication system between the gut and the brain, has become of central importance in Parkinson disease (PD) research over the past 20 years. Aims We aimed to describe the milestones of the gut‐brain axis research in PD and the development of theories proposing the involvement of the ...
Elisa Menozzi+2 more
wiley +1 more source
Summary: Background: Constipation is prevalent worldwide, significantly increasing healthcare costs and diminishing the quality of life in children affected.
Felicia Djurijanto+8 more
doaj
Constipation in Childhood Coeliac Disease [PDF]
B Egan‐Mitchell, B McNicholl
openalex +1 more source
Aqueous extracts of <i>Elsholtzia ciliata</i> and <i>Hovenia dulcis</i> ameliorate loperamide-induced constipation in mice by promoting intestinal peristalsis and barrier function and the abundance of intestinal beneficial bacteria. [PDF]
Wu J, Xin Q, Wang S, Zhang X, Jiang C.
europepmc +1 more source
What is the best way to manage neurogenic bowel dysfunction? [PDF]
McClurg, Doreen, Norton, Christine
core +2 more sources