Results 41 to 50 of about 337,411 (342)

Approaches to managing chronic constipation in older people within the community setting [PDF]

, 2015
Constipation is a common presenting problem within the community setting, but its treatment is often unsatisfactory. It is important for nurses to remember that constipation is a symptom and not a disease.
Bardsley, A.
core   +1 more source

Bio-mechanical risk factors for uterine prolapse among women living in the hills of west Nepal: A case-control study. [PDF]

, 2020
OBJECTIVE:To investigate whether heavy load carrying, wearing a patuka, and body position at work are risk factors for uterine prolapse among Nepali women.
Bates, Michael N, Devkota, Hridaya Raj, Ghimire, Dirgha J, Harris, Carisa, Prata, Ndola, Sijali, Tula Ram   +5 more
core   +2 more sources

Berberine–cinnamic acid co‐crystal effect in ameliorating hyperlipidemia might be regulated through the PI3K/AKT/mTOR/SREBP‐1 signaling pathway

FEBS Open Bio, EarlyView.
Berberine–cinnamic acid co‐crystal (BBR‐CA) inhibits the phosphorylation of the phosphatidylinositol 3‐kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR) pathway, suppressing the transfer of pre‐sterol regulatory element‐binding proteins‐1 (SREBP‐1) from the endoplasmic reticulum to the nucleus. This results in a decrease in the expression level of
Wenheng Gao, Yunlong Li, Lihua Chen, Wenshuo Yang, Yong He, Ye Yang, Dengke Yin, Song Tan   +7 more
wiley   +1 more source

The Efficacy of Peripheral Opioid Antagonists in Opioid-Induced Constipation and Postoperative Ileus: A Systematic Review of the Literature. [PDF]

, 2017
Opioid-induced constipation has a negative impact on quality of life for patients with chronic pain and can affect more than a third of patients. A related but separate entity is postoperative ileus, which is an abnormal pattern of gastrointestinal ...
Baratta, Jaime L., Grant, Alexander E., McNulty, Stephen E., Schwenk, Eric S., Torjman, Marc C., Viscusi, Eugene R.   +5 more
core   +1 more source

INF2‐Related Charcot–Marie–Tooth Disease in a Japanese Cohort: Genetic and Clinical Insights

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background INF2 mutations cause focal segmental glomerulosclerosis (FSGS) and Charcot–Marie–Tooth disease (CMT). Accurate genetic diagnosis is critical, as INF2‐related FSGS is typically resistant to immunotherapy yet rarely recurs after transplantation, and its associated neuropathy can mimic treatable immune‐mediated disorders such as ...
Chikashi Yano, Masahiro Ando, Yujiro Higuchi, Jun‐Hui Yuan, Akiko Yoshimura, Takahiro Hobara, Risa Nagatomo, Fumikazu Kojima, Yu Hiramatsu, Satoshi Nozuma, Tomonori Nakamura, Yusuke Sakiyama, Chika Matsuoka, Toru Yamashita, Takashi Kimura, Ayako Miyazaki, Chinatsu Kinjo, Kenji Yokochi, Nanami Yamanaka, Nozomu Matsuda, Tomoki Suichi, Yoshiyuki Hanaoka, Haruka Kojima, Kenichi Todo, Hiroyuki Ishiura, Jun Mitsui, Shoji Tsuji, Hiroshi Takashima   +27 more
wiley   +1 more source

Prevalence of constipation among central region population, Riyadh and Qassim provinces, Saudi Arabia, 2018-2019

Journal of Family Medicine and Primary Care, 2019
Background: Due to the lack of data and studies concerning the prevalence of constipation in Saudi Arabia, this study aimed at determining the level of prevalence among central region population in Saudi Arabia, specifically in Riyadh and Qassim ...
Mohammed Alhassan, Abdulaziz Alhassan, Abdulaziz Alfarhood, Khalid Alotaibi, Nashmi Alrashidy, Khalid Alshalhoub, Meshal Almeshal   +6 more
doaj   +1 more source

Limited post-operative narcotic use in elective laparoscopic cholecystectomy [PDF]

, 2017
Purpose: To limit narcotics use Cochrane review: multiple studies have shown postoperative pain can be managed with non-narcotic meds with good outcome Less medication related side effects:N/V, constipation, disorientation Prevents substance addiction ...
Josloff, MD, Robert, Noonan, MD, Kristin, Olszewski, MD, Tanya, Senthil-Kumar, MD, Prabhu   +3 more
core   +1 more source

Changes in neuromuscular structure and functions of human colon during ageing are region-dependent [PDF]

, 2018
Objective: To determine if human colonic neuromuscular functions decline with increasing age.Design: Looking for non-specific changes in neuromuscular function, a standard burst of electrical field stimulation (EFS) was used to evoke neuronally mediated (
Ahmed, Shafi, Broad, John, Carroll, Rebecca, Chin-Aleong, Joanne, Darreh-Shori, Taher, Elahi, Shezan, Karami, Azadeh, Knowles, Charles H., Kung, Victor W. S., Martin, Joanne E., Palmer, Alexandra, Saffrey, M. Jill, Sanger, Gareth John, Thaha, Mohamed Adhnan   +13 more
core   +2 more sources

Will Memantine Exacerbate Seizures in People With Epilepsy? A Prospective Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate whether add‐on memantine would exacerbate seizures in people with epilepsy. Methods This was a prospective cohort study. People with epilepsy diagnosed with cognitive impairment were consecutively invited. Those who agreed were followed up for at least 24 weeks.
Peiyu Wang, Lu Lu, Hui Gao, Qi Zhang, Jing Xiao, Josemir W. Sander, Weixi Xiong, Dong Zhou   +7 more
wiley   +1 more source

Intestinal microbiome changes and mechanisms of maintenance hemodialysis patients with constipation

Frontiers in Cellular and Infection Microbiology
BackgroundConstipation is a common symptom in maintenance hemodialysis patients and greatly affects the quality of survival of hemodialysis patients. Fecal microbiota transplantation and probiotics are feasible treatments for functional constipation, but
Aiping Zhang, Shilei Chen, Yanqin Zhu, Mengqi Wu, Bin Lu, Xin Zhou, Yan Zhu, Xinyu Xu, Hong Liu, Fenggui Zhu, Riyang Lin, Riyang Lin   +11 more
doaj   +1 more source