Results 111 to 120 of about 10,381 (250)

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

open access: yesFEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay   +2 more
wiley   +1 more source

Acquiring V2 in declarative sentences and constituent questions in German as a second language

open access: yes, 2020
German is a well-studied language within the PT framework and its predecessor, the Multidimensional Model (cf. Meisel, Clahsen & Pienemann 1981; Clahsen, Meisel & Pienemann 1983; Pienemann 1981, 1984, 1989, 1998; Clahsen 1984; Ellis 1989; Boss 1996, 2004;
Jansen, Louise, Di Biase, Bruno
core  

«Analyse des slogans écrits du «Hirak algérien

open access: yesمجلة الآداب و العلوم الإجتماعية
Notre recherche vise à analyser les slogans écrits du Hirak algérien afin de mieux cerner le fonctionnement de l’écriture revendicatrice. Pour ce faire, il a fallu répondre aux questions suivantes: Pour qui, pourquoi et à qui s’adressent ces slogans? De
وريدة هدوش
doaj  

Small RNA pathways in mammalian oocytes

open access: yesFEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

The American Tradition of Constituent Power

open access: yes, 2017
How do “the people” exercise their revolutionary right to replace the existing constitutional order? The conventional answer is that the people act through specially elected constitution-making bodies like constitutional conventions. But what powers must
Partlett, W
core   +1 more source

How phagocytic cells kill bacteria: Lessons from a professional killer

open access: yesFEBS Open Bio, EarlyView.
How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Whole Earth Machines: Human-Machine Communication for a Green Transition

open access: yesHuman-Machine Communication Journal
The climate crisis of the 21st century represents an existential risk to humanity and biodiversity, posing essential questions of how communication may serve to coordinate mitigation of and adaptation to climate change.
Klaus Bruhn Jensen
doaj   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

Représentation(s) et luttes des Latinxs queers dans les reboots, remakes et revivals LGBTQ+ états-uniens

open access: yesTextes & Contextes
Cet article se propose d’étudier la représentation des Latinxs LGBTQ+ dans trois séries états-uniennes contemporaines : Pose (FX 2018-2021), Les Chroniques de San Francisco (Netflix 2019) et Queer as Folk (Peacock
Alexandre Adouard
doaj   +1 more source

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