Results 281 to 290 of about 1,871,925 (346)

Study on a Traditional Chinese Medicine constitution recognition model using tongue image characteristics and deep learning: a prospective dual-center investigation. [PDF]

Chin Med
Liu Y, Fan L, Zhao M, Wei D, Zhao M, Dong Y, Zhang X.   +6 more
europepmc   +1 more source

Overexpression of CDT1 inhibits cell cycle progression at S phase by interacting with the mini‐chromosome maintenance complex and causes DNA damage

FEBS Open Bio, EarlyView.
CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama, Nonoka Takayama, Rina Tanaka, Yuuki Arai, Yohko Yamaguchi, Yuko Nawata, Yutaro Azuma, Shusuke Tada   +7 more
wiley   +1 more source

Impact of Lipid Bilayer Composition and Physicochemical Properties on Constitution of a Transmembrane Helical Peptide into Exosome-Mimetic Vesicles. [PDF]

Mol Pharm
Tsutsumi S, Takechi-Haraya Y, Abe Y, Kawakami K.   +3 more
europepmc   +1 more source

A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms

FEBS Open Bio, EarlyView.
We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley   +1 more source

Feature Selection and Prediction of Pediatric <i>Tuina</i> in Attention Deficit/Hyperactivity Disorder Management: A Machine Learning Approach Based on Parent-Reported Children's Constitution. [PDF]

Bioengineering (Basel)
Chen SC, Wu GT, Li H, Zhang X, Li ZH, Wong PM, Han LF, Qin J, Lo KC, Yeung WF, Ren G.   +10 more
europepmc   +1 more source

HSP70 governs permeability and mechanotransduction in primary human endothelial cells

FEBS Open Bio, EarlyView.
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez, Everton G. Melo, Isadora C. B. Pavan, Percíllia V. S. Oliveira, Luiza B. C. T. Coimbra, Thaís L. S. Araujo   +5 more
wiley   +1 more source

Realising governmentality: Pastoral power, governmental discourse and the (re)constitution of subjectivities

, 2018
Graham Martin, Justin Waring
openalex   +2 more sources

"Covering For Our City Blight": Kudzu and Public Health in Atlanta, 1979-1994. [PDF]

J Hist Med Allied Sci
Reilly K.
europepmc   +1 more source

Cloning, expression, purification, and structural modeling of the Chandipura virus matrix protein

FEBS Open Bio, EarlyView.
This research protocol offers a guide for the cloning, expression, and purification of the Chandipura virus matrix protein using E. coli. It also includes a step‐by‐step procedure for cloning, expressing, and conducting fluorescence imaging of GFP‐fused Chandipura virus matrix protein in mammalian cell lines.
Mariana Grieben
wiley   +1 more source

Associations between Traditional Chinese Medicine Body Constitution and Cardiovascular Disease Risk in a White population. [PDF]

Aging Health Res
Shu L, Yin X, Zhu X, Zhao J, Deng X, Shubin YE, Murff HJ, Ness RM, Yu C, Shrubsole MJ, Dai Q.   +10 more
europepmc   +1 more source