Results 31 to 40 of about 14,307,889 (304)

Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin   +17 more
wiley   +1 more source

The illiberal abuse of constitutional courts in Europe [PDF]

open access: yes, 2019
Legal constitutionalism – Political constitutionalism – Emergence of illiberal constitutionalism as a tertium genus – Examination of constitutional courts under three illiberal governments: Poland, Hungary, and Turkey – Illiberal governments’ strategies ...
Castillo Ortiz, P.J.
core   +1 more source

Bone and Soft Tissue Neoplasms in Infants Versus Older Children: A Report From the Cancer in Young People in Canada Program

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Infant bone and soft tissue neoplasms present distinct clinical challenges and lack large‐scale data to inform treatment decisions. This study aims to characterize bone and soft tissue neoplasms in infants in Canada and to compare their outcomes with those of older pediatric patients.
Samuel Sassine   +21 more
wiley   +1 more source

Responsive Judicial Review in Canada: Reflections on the Notwithstanding Clause and Beyond [PDF]

open access: yes
This essay responds to the preceding papers in the special issue, which think through the implications of Responsive Judicial Review for Canadian debates on a range of questions, including: the scope of section 33 of the Charter, the role of unwritten ...
Dixon, Rosalind
core   +1 more source

Development of a Disease Activity Index for the Assessment of VEXAS Syndrome (VEXAS‐DAI)

open access: yesArthritis Care &Research, EarlyView.
Objective Vacuoles, E1 enzyme, X‐linked, autoinflammatory, somatic syndrome (VEXAS) syndrome is characterized by a complex spectrum of inflammatory and hematologic manifestations. Clinical research to identify effective therapies is urgently needed but is hindered by the lack of validated outcome measures.
Kevin Byram   +25 more
wiley   +1 more source

Deconstructing City of Toronto: Unwritten Constitutional Principles and Responsive Judicial Review [PDF]

open access: yes
This article distinguishes between two conceptions of unwritten constitutional principles, which it refers to as the uncrossable thresholds and symbiotic conceptions.
Mailey, Richard
core   +1 more source

Real‐World Effectiveness and Safety of Secukinumab in Giant Cell Arteritis: An Italian Multicenter Cohort Study

open access: yesArthritis Care &Research, EarlyView.
Objective The objective of this study was to evaluate the real‐world effectiveness and safety of secukinumab in patients with giant cell arteritis (GCA). Methods This multicenter retrospective study included patients with GCA who received secukinumab at 14 Italian centers with at least six months of follow‐up.
Luca Iorio   +28 more
wiley   +1 more source

Constitutional Review in Hong Kong under the ‘One Country, Two Systems’ Framework: An Inquiry into its Establishment, Justification and Scope [PDF]

open access: yes, 2013
This thesis enquires into the establishment, justification and scope of constitutional review in Hong Kong against the unique constitutional order of "One Country, Two Systems" established in Hong Kong after its return to China in 1997.
LI, GUANGXIANG
core  

Editors’ Introduction: Responsive Judicial Review [PDF]

open access: yes
This editorial intro explains the origins of the special issue and provides a short synopsis of the papers within it. It is written by the co-organizers of the Responsive Judicial Review workshop, Richard Mailey (Centre for Constitutional Studies) and ...
MacDonnell, Vanessa, Mailey, Richard
core   +1 more source

High‐Entropy Alloy Interlayers Toward Advanced Joining for High‐Performance Structural Applications: Current Progress and Emerging Challenges

open access: yesAdvanced Engineering Materials, EarlyView.
HEA interlayers offer a versatile route for joining high‐performance structural materials. Their compositional and structural design regulates interfacial reactions, suppresses brittle IMCs, and improves metallurgical bonding. Sandwich interlayers further integrate defect healing with precipitation strengthening, enabling improved strength–ductility ...
Lin Yuan   +4 more
wiley   +1 more source

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