Results 111 to 120 of about 4,302 (292)

A multilevel perspective on MSH6‐associated Lynch syndrome: Integrating molecular, biological, and clinical insights

International Journal of Cancer, EarlyView.
Abstract Lynch syndrome (LS) is the most common hereditary colorectal cancer syndrome, caused by a germline pathogenic variant in one of the mismatch repair (MMR) genes. Among these, MSH6‐associated LS represents a distinct subtype with unique molecular and clinical characteristics.
Salwa Ben Yahia, Anne‐Sophie van der Werf‐'t Lam, Madalina Cabuta, Maartje Nielsen, Noah C. Helderman   +4 more
wiley   +1 more source

Human biomarker navigator

iMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li, Qian Zhang, Zijie Wang, Zeping Gui, Jing Liu, Jingda Li, Maojun Jiang, Zukang Chang, Qingqing Han, Bendong Yang, Tariq Saeed, Jun Li, Jinghan Jia, Chenghu Song, Tong Shao, Tianhuan Peng, Xueying Zhang, Pingping Guo, Jun Luo, Gangao Yang, Yuan Wan, Gokhan Zengin, Quan Yuan, Lingru Li, Xiaohui Fan, Yang Luo, Lvyun Zhu, Yanfei Zheng, Wenjun Mao, Wenlong Sun   +29 more
wiley   +1 more source

How not to write a constitution: lessons from Chile. [PDF]

Public Choice, 2023
Larrain G, Negretto G, Voigt S.
europepmc   +1 more source

The Predictive Accuracy of Prenatal Ultrasound for Macrosomia—A Retrospective Cohort Study

Journal of Clinical Ultrasound, EarlyView.
Third‐trimester fetal weight estimation has limited predictive accuracy for neonatal macrosomia (low sensitivity and PPV) but may influence clinical decisions as it is strongly associated with labor induction. Prenatal macrosomia diagnosis should therefore be cautiously interpreted. ABSTRACT Objectives This study aimed to evaluate the accuracy of third‐
Isabella Abati, Mor Huri, Noemi Strambi, Laura Capiluppi, Silvia Giovinale, Viola Seravalli, Mariarosaria Di Tommaso   +6 more
wiley   +1 more source

The Constitutionalization of the European Union: Explaning the Parliamentarization and Institutionalization of Human Rights [PDF]

, 2005
: Parliamentarization and the institutionalization of human rights are two processes of constitutionalization in the EU that constitute a puzzle for explanations inspired by both rationalist and constructivist institutionalism. We propose toanalyze these
Schimmelfennig, Frank, Rittberger, Berthold   +1 more
core   +1 more source

The 3Rs Principle in Animal Experimentation: A Legal Review of the State of the Art in Europe and the Case in Italy. [PDF]

BioTech (Basel), 2021
Maestri E.
europepmc   +1 more source

Clinical progress note: Mumps

Journal of Hospital Medicine, EarlyView.
Abstract Mumps was a common childhood viral illness before the implementation of the measles, mumps, and rubella (MMR) vaccination in 1967. There was a significant decrease in mumps cases in the postvaccine era; however, there has been an increase in outbreaks in the United States over the past two decades.
Sarah Ludvigsen, Mati Segev
wiley   +1 more source

Old disease, new twist

Journal of Hospital Medicine, EarlyView.
Abstract An 81‐year‐old man with a history of high‐grade urothelial carcinoma of the bladder and ureter on treatment with atezolizumab and tiragolumab presented to the emergency department with 5 months of malaise, generalized weakness, and fatigue and 2 weeks of subjective fevers. One month prior to presentation, he received an empiric 9‐day course of
Hadi Roudsari, Gurpreet Dhaliwal, Anand D. Jagannath, Alan H. Baik, Sam Brondfield   +4 more
wiley   +1 more source

From industrial to digital citizenship: rethinking social rights in cyberspace. [PDF]

Theory Soc, 2023
Tomasello F.
europepmc   +1 more source

Appropriate screening strategy and timely referral in suspected pediatric inflammatory bowel disease: Impact on diagnostic delay and severity at presentation

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Pediatric‐onset inflammatory bowel disease (pIBD) often presents with nonspecific symptoms, contributing to diagnostic delay (DD) and increased morbidity. Despite the importance of referral quality, diagnostic pathways in pIBD have rarely been evaluated.
Francesca Borgiani, Mario Brusco, Elisa Franceschini, Maria Elena Lionetti, Simona Gatti   +4 more
wiley   +1 more source