Results 31 to 40 of about 13,201 (298)

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina   +11 more
wiley   +1 more source

The 2020 U.S. Supreme Court and Political Identity

open access: yesPoliteja, 2020
This article aims to determine current political identity of the U.S. Supreme Court by analyzing the process of appointment of its recent Justices and their ideology.
Paweł Laidler
doaj   +1 more source

Combined Process‐ and Phase‐Field‐Simulation to Predict the Microstructure of Single‐Crystal Ni‐Based Superalloys

open access: yesAdvanced Engineering Materials, EarlyView.
A combined finite element and phase‐field approach predicts the evolution of microstructure during the directional solidification of Ni‐based superalloys. The model reveals how withdrawal rate, temperature gradient, and wall thickness control the dendrite spacing, highlighting the strong effect of surface regions in thin sections where dendrite growth ...
Sean Böhm   +3 more
wiley   +1 more source

Global Constitutionalism: the Theory of the Global Legal Order or a New Political Ideology?

open access: yesHistoria provinciae: журнал региональной истории, 2020
The idea of the global legal order, accompanying humanity throughout the whole history of its existence, has acquired practical relevance in the recent period as a tool for resolving the contradictions of globalization: world integration and regional ...
Andrei N. Medushevskii
doaj   +1 more source

Azaporphyrinoid‐Based Photo‐ and Electroactive Architectures for Advanced Functional Materials

open access: yesAdvanced Materials, EarlyView.
A long‐standing collaboration between the Torres and Guldi groups has yielded diverse azaporphyrinoid‐based donor‐acceptor nanohybrids with promising applications in solar energy conversion. This conspectus highlights key molecular platforms and structure‐function relationships that govern light and charge management, supporting the rational design of ...
Jorge Labella   +3 more
wiley   +1 more source

Constitutionalization and Entrepreneurship: Explaining Increased EU Steering of Renewables Support Schemes

open access: yesPolitics and Governance, 2019
This article sheds light on two under-researched issue areas: the energy policy-shaping role of the Court of Justice of the European Union (CJEU) and how constitutionalization of EU state aid law gives the European Commission (Commission) increased ...
Elin Lerum Boasson
doaj   +1 more source

Ethical Precision in Nanoscale Brain Interfacing

open access: yesAdvanced Science, EarlyView.
As brain interfaces approach the nanoscale, precision no longer only measures—it knows, predicts, and potentially reshapes the mind. This work argues that traditional ethics fails under such conditions and proposes a shift toward continuous, operation‐based governance using the recovery–discovery framework to track, constrain, and responsibly steer ...
Guilherme Wood
wiley   +1 more source

Is Hyperpluralism Compatible with Dualist Constitutionalism? On Alessandro Ferrara's Conception of Multivariate Democratic Polity [PDF]

open access: yes, 2017
In this essay I first set out the advantages the " multivariate democratic polity " framework proposed by Ferrara offers in comparison to other more consensus-based notions of democratic legitimacy.
Testa, Italo
core  

Heterogeneous Visible‐Light Photocatalysis in Continuous‐Flow: A Synergistic Strategy for Challenging Trifluoromethylation of α, α‐Diaryl Allylic Alcohols via 1,2‐aryl Migration

open access: yesAdvanced Science, EarlyView.
A continuous‐flow photocatalytic strategy is presented for the efficient synthesis of β‐trifluoromethyl ketones under visible light. Using a recyclable solid photocatalyst and an inexpensive CF3 source, the method enables rapid reactions, easy scale‐up, and smooth integration into multistep flow synthesis of bioactive molecules.
Peiwen Liu   +3 more
wiley   +1 more source

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