Results 41 to 50 of about 732,139 (286)

The Efficacy and Safety of Bevacizumab/Irinotecan/Temozolomide (BIT) for Relapsed/Refractory Neuroblastoma: The UK Children's Cancer and Leukaemia Group Experience

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Patients with high‐risk neuroblastoma who either are refractory to induction chemotherapy or relapse following multi‐modal treatment have a dismal prognosis. Based on data from the BEACON trial, since 2021 the UK national guidelines recommend bevacizumab, irinotecan, and temozolomide (BIT) for patients with relapsed/refractory ...
Thomas J. Jackson   +20 more
wiley   +1 more source

Multi-hop Diffusion LMS for Energy-constrained Distributed Estimation

open access: yes, 2014
We propose a multi-hop diffusion strategy for a sensor network to perform distributed least mean-squares (LMS) estimation under local and network-wide energy constraints.
Hu, Wuhua, Tay, Wee Peng
core   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

Estimation of DOA for Noncircular Signals via Vandermonde Constrained Parallel Factor Analysis

open access: yesInternational Journal of Antennas and Propagation, 2018
We provide a complete study on the direction-of-arrival (DOA) estimation of noncircular (NC) signals for uniform linear array (ULA) via Vandermonde constrained parallel factor (PARAFAC) analysis.
Heyun Lin   +3 more
doaj   +1 more source

Constrained Adjusted Maximum a Posteriori Estimation of Bayesian Network Parameters

open access: yesEntropy, 2021
Maximum a posteriori estimation (MAP) with Dirichlet prior has been shown to be effective in improving the parameter learning of Bayesian networks when the available data are insufficient.
Ruohai Di   +3 more
doaj   +1 more source

Geometric approach to Fletcher's ideal penalty function [PDF]

open access: yes, 1995
Original article can be found at: www.springerlink.com Copyright Springer. [Originally produced as UH Technical Report 280, 1993]In this note, we derive a geometric formulation of an ideal penalty function for equality constrained problems.
Christianson, B.
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Parameter Estimation of Electromechanical Oscillation Based on a Constrained EKF with C&I-PSO

open access: yesEnergies, 2018
By combining together the extended Kalman filter with a newly developed C&I particle swarm optimization algorithm (C&I-PSO), a novel estimation method is proposed for parameter estimation of electromechanical oscillation, in which critical ...
Yonghui Sun   +5 more
doaj   +1 more source

Distributed Moving Horizon Fusion Estimation for Nonlinear Constrained Uncertain Systems

open access: yesMathematics, 2023
This paper studies the state estimation of a class of distributed nonlinear systems. A new robust distributed moving horizon fusion estimation (DMHFE) method is proposed to deal with the norm-bounded uncertainties and guarantee the estimation performance.
Shoudong Wang, Binqiang Xue
doaj   +1 more source

Enhancing Compressed Sensing 4D Photoacoustic Tomography by Simultaneous Motion Estimation [PDF]

open access: yes, 2018
A crucial limitation of current high-resolution 3D photoacoustic tomography (PAT) devices that employ sequential scanning is their long acquisition time.
Arridge, Simon   +6 more
core   +3 more sources

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