Results 211 to 220 of about 7,132 (254)

A Panel of Circulating Exosomal sncRNAs Associated With Lung Cancer Risk up to 10 Years in Advance

Advanced Science, EarlyView.
Lung cancer is often diagnosed too late, and current screening overlooks many people at risk. In a long‐term study of smokers, a panel of small non‐coding RNAs carried in blood exosomes signals elevated lung cancer risk up to ten years before diagnosis, pointing toward a blood‐based tool for earlier risk detection.
Zhuokun Feng, Masaki Nasu, Ayman Abdul‐Ghani, Yu Chen, Shaoqiu Chen, Isam Mohd Ibrahim, Hanqiu Zhang, Lauren Higa, Zitong Gao, Hua Yang, Raphael Bueno, Loïc Le Marchand, Youping Deng   +12 more
wiley   +1 more source

Engineering a 660 nm‐Responsive Optogenetic Inducer of Pyroptosis for Precision Cancer Therapy

Advanced Science, EarlyView.
This study reports a bioorthogonal pyroptosis inducer, PyroRACS. By using a red‐light‐responsive Cre‐On genetic switch to control the expression of highly cytotoxic GSDMDNT, PyroRACS enables the artificial induction of pyroptosis with precise spatiotemporal control.
Mengkai Zhang, Zhichao Li, Yonghao Ma, Yangyang Sun, Wei Chen, Weiren Huang   +5 more
wiley   +1 more source

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Constraint-induced movement therapy: from history to plasticity

Expert Review of Neurotherapeutics, 2012
Constraint-induced movement therapy (CIMT) is a rehabilitative strategy applied primarily to the post-stroke population to increase the functional use of the neurologically weaker upper extremity through massed practice, while restraining the lesser involved upper extremity.
Stacy Fritz, Steven Wolf
exaly   +3 more sources

Telehealth and Constraint-Induced Movement Therapy (CIMT)

Clinical Gerontologist, 2007
Abstract Stroke is the leading cause of disability in the United States. Stroke survivors often experience motor sequelae characterized by hemiparesis in the upper extremity contralateral to the brain lesion. Constraint-Induced Movement Therapy (CIMT) is an effective treatment for post-stroke hemiparesis.
Stacy Fritz, Robert Glueckauf, Kathye E Light   +2 more
exaly   +2 more sources

Constraint-induced movement therapy: a narrative review

Physiotherapy, 2008
Abstract Objectives To identify factors relevant to implementing constraint-induced movement therapy (CIMT) within the clinical setting. Data sources AMED (1995–January 2007), CINHAL (1982–January 2007), Medline (1996–January 2007) and EMBASE (1996–January 2007) were searched to identify relevant studies.
exaly   +2 more sources

The neural basis of constraint-induced movement therapy

Current Opinion in Neurology, 2009
This review describes our current understanding of the changes in brain function and structure that occur in response to an intensive form of motor rehabilitation, constraint-induced movement therapy (CIMT), that has been shown to be efficacious in promoting motor function of the paretic upper limb of stroke patients.Studies using transcranial magnetic
George F, Wittenberg, Judith D, Schaechter   +1 more
openaire   +2 more sources

Methods to improve constraint-induced movement therapy

NeuroRehabilitation, 2009
In global terms, cerebrovascular stroke is the leading cause of long-term disability. Despite improved acute phase management of stroke, the majority of survivors are disabled and many require effective rehabilitation. Constraint-induced movement therapy (CIMT) is one of the recently emerging therapies for subjects with stroke.
Ina M, Tarkka, Mervi, Könönen
openaire   +2 more sources

Optimizing Constraint-Induced Movement Therapy for Children With Cerebral Palsy

Pediatrics, 2021
* Abbreviations: CIMT — : constraint-induced movement therapy CP — : cerebral palsy Constraint-induced movement therapy (CIMT) is one of the best studied treatments for hemiplegic cerebral palsy (CP), which is one of the most common types of CP and is estimated to affect 1 per every 1000 children.1,2 Therefore, optimizing the ...
Alyssa E, Smith, Bhooma, Aravamuthan
openaire   +2 more sources

Barriers to the Implementation of Constraint-Induced Movement Therapy Into Practice

Topics in Stroke Rehabilitation, 2012
Constraint-induced movement therapy (CIMT) has been studied for many years in the treatment of the hemiplegic upper extremity (UE). However, there has been limited adoption of the protocol in daily practice.In this article, we review the CIMT literature specifically for meta-analysis, randomized controlled trials (RCTs), recent case reports, case ...
Ricardo, Viana, Robert, Teasell
openaire   +2 more sources

Constraint-Induced Movement Therapy for Cerebral Palsy: A Randomized Trial

Pediatrics, 2021
OBJECTIVES With the Children with Hemiparesis Arm and Hand Movement Project (CHAMP) multisite factorial randomized controlled trial, we compared 2 doses and 2 constraint types of constraint-induced movement therapy (CIMT) to usual customary treatment (UCT).
Sharon Landesman, Ramey, Stephanie C, DeLuca, Richard D, Stevenson, Mark, Conaway, Amy R, Darragh, Warren, Lo   +5 more
openaire   +2 more sources