Results 101 to 110 of about 564,271 (287)

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Mangasarian–Fromovitz-type constraint qualification and optimality conditions for smooth infinite programming problems

Advances in Nonlinear Analysis
We introduce a constraint qualification condition GPMFCQ for smooth infinite programming problems, where the nonlinear operator defining the equality constraints has nonsurjective derivative at the local minimum.
Bednarczuk Ewa M., Leśniewski Krzysztof W., Rutkowski Krzysztof E.   +2 more
doaj   +1 more source

Constraint Qualifications and Optimality Criteria for Nonsmooth Multiobjective Mathematical Programming Problems with Equilibrium Constraints on Hadamard Manifolds

Axioms
Nonsmooth multiobjective mathematical programming problems with equilibrium constraints (NMMPEC) are studied in this article in the Hadamard manifold setting.
B. B. Upadhyay, Arnav Ghosh, I. M. Stancu-Minasian, Andreea Mădălina Rusu-Stancu   +3 more
doaj   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

Optimality Conditions for Mathematical Programs with Vanishing Constraints Using Directional Convexificators

Axioms
This article deals with mathematical programs with vanishing constraints (MPVCs) involving lower semi-continuous functions. We introduce generalized Abadie constraint qualification (ACQ) and MPVC-ACQ in terms of directional convexificators and derive ...
Ram Narayan Mohapatra, Prachi Sachan, Vivek Laha   +2 more
doaj   +1 more source

Determinants of undergraduate bioscience engagement: Validating attendance barriers and classroom spatial behaviour across institutions

FEBS Open Bio, EarlyView.
Student engagement extends beyond simple attendance. Across 891 bioscience students from three universities, attendance behaviour was associated mainly with structural influences, whereas classroom spatial behaviour reflected affective and sensory factors.
Nigel Page, Rachel J. Hunt, Lauren J. Albee, Daniel Berwick, Alison Snape   +4 more
wiley   +1 more source

Five‐Year Outcomes of Laparoscopic Sphincter‐Preserving Surgery for Rectal Cancer: A Prospective Study in Elderly Vietnamese Patients

Aging and Cancer, EarlyView.
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho, Quang Le, Ngoc Thach Tran, Van Viet Ung, Loc Vu   +4 more
wiley   +1 more source

Self‐Regulated Learning Meets AI: Reinterpreting Self‐Regulation, Co‐Regulation, and Socially Shared Regulation in Human–AI Interaction

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Advancing artificial intelligence (AI) has transformed learning and work, yet higher education and professional development programs have not systematically equipped learners for AI‐prevalent environments. This lack of preparation creates uncertainty regarding control, responsibility, trust, and accountability.
Moon‐Heum Cho, Jerusalem Merkebu
wiley   +1 more source

Sequential quadratic programming and constraint qualification

, 2018
Orientador: Maria Aparecida Diniz EhrhardtDissertação (mestrado) - Universidade Estadual de Campinas, Instituto de Matematica, Estatistica e Computação CientificaResumo: Abordando problemas de minimização de funções com restrições nos deparamos com as ...
Nunes, Fernanda Téles
core  

A Duality Framework for Mathematical Programs with Tangential Subdifferentials

Algorithms
The aim of this article is to study duality results for nonsmooth mathematical programs with equilibrium constraints in terms of tangential subdifferentials.
Vandana Singh, Shashi Kant Mishra, Abdelouahed Hamdi   +2 more
doaj   +1 more source