Supramolecular Degraders: An Emerging Paradigm in Targeted Protein Degradation
Dynamic supramolecular assembly reshapes targeted protein degradation by coordinating modular degrader construction, delivery, functional integration, and intracellular assembly or activation across proteasomal, endosomal–lysosomal, and autophagy–lysosomal pathways.
Kongjun Liu +8 more
wiley +1 more source
Safe causal-graph primal-dual multi-agent scheduling for energy- and latency-constrained edge-assisted cognitive radio networks. [PDF]
Kannan T +3 more
europepmc +1 more source
This study elucidates the microstructural evolution at the material interface of Ni‐plated plain‐weave carbon fiber fabric following vacuum heat treatment at 500°C–900°C under different current densities, as well as the mechanism underlying the synergistic enhancement of electromagnetic shielding and ductility.
Wei Cheng +7 more
wiley +1 more source
EVA-centric QUBO optimization for active and reactive power coordination in DLMP-driven distribution systems. [PDF]
Suri V +5 more
europepmc +1 more source
From Sensing Mechanisms to System Co‐Design: Graphene‐Based Sensors and Readout Circuits
This review establishes a unified PS–EQ–RF framework linking graphene sensing mechanisms, native electrical outputs, and output‐specific readout circuits. Voltage‐, current‐, resistance‐, and capacitance‐type sensing systems are systematically classified to guide architecture selection, low‐noise design, system co‐design, and practical integration ...
Jinduo Zhang +5 more
wiley +1 more source
Output Feedback Adaptive Tracking Control for Uncertain Strict-Feedback Nonlinear Systems with Full-State Constraints and Unknown Output Gain. [PDF]
Wang Z +4 more
europepmc +1 more source
Triple‐Level Content‐Addressable Vertical NAND Flash Memory
Commercial triple‐level‐cell V‐NAND flash memory is transformed into a compact content‐addressable memory by directly exploiting its eight threshold‐voltage states. A parity‐split search scheme preserves storage density while enabling reliable multi‐level and don't‐care matching. Parallel word‐line search delivers up to 24‐fold higher throughput and 54.
Sung‐Ho Park +8 more
wiley +1 more source
Improved Pain and Function, Low Complication Rates, and 95% Patient Satisfaction at 2 Years After Medially Stabilized Total Knee Arthroplasty: A Prospective Multicenter Cohort Study. [PDF]
Baré J +4 more
europepmc +1 more source
Potential of Nanoparticle‐Based Phototherapies for Future Treatment of Uveal Melanoma
This review evaluates nanoparticle‐based phototherapies for uveal melanoma, highlighting emerging strategies to enhance tumor targeting, light delivery, and treatment precision. Preclinical data indicate improved efficacy and reduced toxicity, supporting their potential to enhance localized treatment and future translational advances. (Generated by the
Emilie Lambert +8 more
wiley +1 more source
Digital twin optimization of water supply pump stations considering energy use, water hammer, and lifespan. [PDF]
Liu Y, Cheng L, Liu K, Zhou T.
europepmc +1 more source

