Results 41 to 50 of about 1,197,135 (323)

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Separate roles of IQGAP Rng2p in forming and constricting the Schizosaccharomyces pombe cytokinetic contractile ring

open access: yesMolecular Biology of the Cell, 2013
Rng2p is required for both the normal process of contractile ring formation from precursor nodes and an alternative mechanism by which rings form from strands of actin filaments, as well as for ring constriction.
I. Tebbs, T. Pollard
semanticscholar   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

A Stochastic model for dynamics of FtsZ filaments and the formation of Z-ring

open access: yes, 2020
Understanding the mechanisms responsible for the formation and growth of FtsZ polymers and their subsequent formation of the $Z$-ring is important for gaining insight into the cell division in prokaryotic cells.
Kumar, A. V. Anil   +2 more
core   +1 more source

Novel surgical extrication of penile constricting metal ring: A case report

open access: yes, 2014
Introduction: Penile entrapment with strangulation is a unique clinical entity which has remained a challenge because of lack of standard treatment modality.
A. Olajide   +3 more
semanticscholar   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Classifying dynamic contact line modes in drying drops [PDF]

open access: yes, 2015
Although the evaporation mode of sessile droplets is almost universally characterized as either constant contact radius (CCR) or constant contact angle (CCA), here we investigate two alternatives where the contact line speed is either constant or ...
Baldwin, KA, Fairhurst, DJ
core   +1 more source

A metallic ring penile foreign body causing penile strangulation: a rare case report

open access: yesInternational Surgery Journal, 2020
Strangulation of penis is a rare clinical entity, which requires urgent urological management to prevent its devastating outcomes. The treatment of penile strangulation is immediate decompression of the constricted penis to facilitate free blood flow ...
Shivalingaiah Maregowda   +1 more
semanticscholar   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

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