Results 271 to 280 of about 21,873 (292)
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Effect of sodium channel blocker (mexiletine) on pathological ectopic firing pattern in a rat chronic constriction nerve injury model

Journal of Orthopaedic Science, 2005
We studied the efficacy of mexiletine as a sodium channel blocker for neuropathic pain by investigating the effect of mexiletine on the pathological ectopic firing pattern in a chronic constriction nerve injury (CCI) model. The experiment was conducted with 60 male Wistar rats. The CCI model was created by loosely ligating the sciatic nerve.
Satoru, Nakamura, Yuji, Atsuta
openaire   +2 more sources

Abstract 60: Cardiac-specific Deletion of HuR Reduces Pathological Hypertrophy and Ventricular Remodeling Following Transverse Aortic Constriction

Circulation Research, 2015
The RNA binding protein HuR (Human antigen R) interacts with specific AU-rich domains in target mRNAs and is highly expressed in many cell types, including cardiomyocytes. However, the role of HuR in cardiac physiology is largely unknown. Our results show that HuR undergoes cytoplasmic translocation, indicative of its activation, in hypertrophic mouse ...
Michael Tranter   +6 more
openaire   +1 more source

Quantitative assessment of the occurrence of asymmetric and symmetrical maxillary constriction and related pathological conditions

Stomatology for All / International Dental review
Quantitative assessment of the occurrence of asymmetric and symmetrical maxillary constriction and related pathological ...
Kh.R. Khumgaeva   +3 more
openaire   +1 more source

Morphodynamics and pathology of blood vessels II. Morphodynamic study of constriction of umbilical blood vessels and its application to coronary artery disease

International Journal of Angiology, 1996
The morphodynamic changes of the umbilical artery from full distension to total occlusion within 45 seconds of delivery is very striking. On gross examination, the constricted artery shows a small, round, outer contour and reduced external diameter.
Ching Lin   +3 more
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Melatonin protects against the pathological cardiac hypertrophy induced by transverse aortic constriction through activating PGC‐1β: In vivo and in vitro studies

Journal of Pineal Research, 2017
AbstractMelatonin, a circadian molecule secreted by the pineal gland, confers a protective role against cardiac hypertrophy induced by hyperthyroidism, chronic hypoxia, and isoproterenol. However, its role against pressure overload‐induced cardiac hypertrophy and the underlying mechanisms remains elusive.
Mengen Zhai   +19 more
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Malignant carcinoid of the small intestine with metastases to the liver, valvular disease of the right side of the heart (pulmonary stenosis and tricuspid regurgitation without septal defects), peripheral vasomotor symptoms, broncho-constriction, and an unusual type of cyanosis

American Heart Journal, 1954
Abstract 1. 1. A new syndrome is described. Seven definite cases, four probable (Cases 11, 12, 13 and 16) and five with partial or not fully verified symptoms (Cases 3, 4, 5, 6 and 14) are presented. 2. 2. The syndrome consists of carcinoid of the small intestine, metastases to the liver, and in several cases to other parenchymatous organs ...
A, THORSON   +3 more
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Quantifying the Effects of a Constricted Temporal Window in Reinforcer Pathology

2019
Health behaviors, positive and negative, can support or reduce risk for multiple chronic diseases, such as substance use disorder and obesity. These diseases are marked by overconsuming commodities that offer predictable short-term benefits, and neglecting other behaviors with variable long-term benefits (e.g., fast food is enjoyable in the moment ...
openaire   +1 more source

Autoimmunity Associated Pathology of Constrictive Bronchiolitis in Cutaneously Lewisite Exposed Mice

B52. MECHANISMS OF PULMONARY TOXICITY, 2023
R. Surolia   +9 more
openaire   +1 more source

An experimental painful peripheral neuropathy due to nerve constriction. I. Axonal pathology in the sciatic nerve.

Experimental neurology, 1992
A constriction injury to the sciatic nerve of the rat produces a painful peripheral neuropathy that is similar to the conditions seen in man. The pathology of the sciatic nerve in these animals was examined at 10 days postinjury, when the abnormal pain sensations are near maximal severity.
B L, Munger, G J, Bennett, K C, Kajander
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CLINICAL FINDINGS OF PATHOLOGICALLY CONFIRMED CONSTRICTIVE BRONCHIOLITIS IN ACTIVE DUTY SERVICE MEMBERS

Chest, 2022
CONNOR WAKEFIELD   +3 more
openaire   +1 more source

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