Results 151 to 160 of about 169,559 (249)

One‐Size‐Fits‐All: A Universal Binding Site for Single‐Layer Metal Cluster Self‐Assembly

Advanced Science, EarlyView.
A universal strategy enables the formation of single‐layer metal clusters (SLMC) across 21 elements by harnessing vacancy defects as binding sites. Crucially, synthesis occurs without reactive species, preventing site passivation and ensuring strong metal–surface bonding.
Emerson C. Kohlrausch, Sadegh Ghaderzadeh, Gazi N. Aliev, Ilya Popov, Fatmah Saad, Eman Alharbi, Quentin M. Ramasse, Graham A. Rance, Mohsen Danaie, Madasamy Thangamuthu, Mathew Young, Richard Plummer, David J. Morgan, Wolfgang Theis, Elena Besley, Andrei N. Khlobystov, Jesum Alves Fernandes   +16 more
wiley   +1 more source

Hybrid protein-ligand binding residue prediction with protein language models: does the structure matter? [PDF]

Bioinformatics
Gamouh H, Novotný M, Hoksza D.
europepmc   +1 more source

SCORCH2: A Generalized Heterogeneous Consensus Model for High‐Enrichment Interaction‐Based Virtual Screening

Advanced Science, EarlyView.
Researchers developed SCORCH2, an advanced machine‐learning scoring function for virtual screening that combines two complementary XGBoost models to re‐evaluate protein‐ligand binding plausibility. The method demonstrates superior performance on standard benchmarks, shows excellent generalization to previously unseen protein targets, and provides ...
Lin Chen, Vincent Blay, Pedro J. Ballester, Douglas R. Houston   +3 more
wiley   +1 more source

Integrating AI and CRISPR Cas13a for rapid detection of tomato brown rugose fruit virus. [PDF]

Sci Rep
Karimi M, Ghorbani A, Niazi A, Rostami M, Tahmasebi A.   +4 more
europepmc   +1 more source

MoMtg1 Acts as a Novel Transcriptional Repressor of MoSwi6 During Appressorium‐Mediated Penetration in the Rice Blast Fungus

Advanced Science, EarlyView.
Appressoria are specialized penetration structures for many plant pathogenic fungi, demanding precise cell cycle control. This study unveils MoMtg1 as a transcriptional repressor of MoSwi6, orchestrating MoCYC1 expression during turgor‐driven cell cycle progression to enable appressorium‐mediated penetration. Moreover, a small‐molecule inhibitor ZS1619
Xingyu Wang, Ting Zhang, Qi Li, Chang‐An Ji, Lin Huang, Mingzhi Zhang, Leiyun Yang, Xinyu Liu, Muxing Liu, Gang Li, Zhengguang Zhang, Haifeng Zhang   +11 more
wiley   +1 more source

Advantages of two quantum programming platforms in quantum computing and quantum chemistry. [PDF]

J Cheminform
Wang PH, Wu WY, Lee CY, Hong JC, Tseng YJ.   +4 more
europepmc   +1 more source

Hinst: Human‐Like Interactive Instinct Enables Robots to Robustly Accomplish Universal Tasks

Advanced Science, EarlyView.
Aiming at current robot limitations of poor flexibility, poor practicality, and poor universality in task accomplishment, the authors report a human‐like interactive instinct (Hinst) and an anthropomorphic robotic system architecture. The Hinst greatly enhances the efficiency and the success rate of robotic manipulation, skill learning, and task ...
Zijian Liao, Qian Mao, Yichen Qin, Jinfeng Yuan, Rong Zhu   +4 more
wiley   +1 more source

Rodin: a streamlined metabolomics data analysis and visualization tool. [PDF]

Bioinform Adv
Minasenko B, Wang D, Cirillo P, Krigbaum N, Cohn B, Jones DP, Collins JM, Hu X.   +7 more
europepmc   +1 more source

Interpretation of RNA Universe and Coding Potential Using IntRNA

Advanced Science, EarlyView.
This study constructs a multi‐channel deep learning framework IntRNA to interpret RNA universe and coding potential. IntRNA consistently performed the best among existing methods in various benchmarks. Moreover, IntRNA’s interpretability is also validated by real‐world analysis, which found some features indicating long‐distance contact between ...
Yunxia Wang, Minjie Mou, Shijie Huang, Wei Zhang, Ziqi Pan, Jing Tang, Yihao Wang, Qingxia Yang, Feng Zhu   +8 more
wiley   +1 more source

Transposon-directed insertion-site sequencing (TraDIS) analysis of <i>Enterococcus faecium</i> using nanopore sequencing and a WebAssembly analysis platform. [PDF]

Microbiol Spectr
Krause AL, Wirth W, Turner AM, Judd L, Li L, van Schaik W, Howden BP, Carter GP, Seemann T, Wick R, Stinear TP, Buultjens AH, Monk IR.   +12 more
europepmc   +1 more source