Results 161 to 170 of about 416,163 (244)

PUCHIK: A Python Package To Analyze Molecular Dynamics Simulations of Aspherical Nanoparticles. [PDF]

J Chem Inf Model
Ishkhanyan H, Santana-Bonilla A, Lorenz CD.   +2 more
europepmc   +1 more source

Targeting miRNA‐1a and miRNA‐15b: A Novel Combinatorial Strategy to Drive Adult Cardiac Regeneration

Advanced Science, EarlyView.
The article explores a novel therapeutic strategy for cardiac regeneration by targeting miRNA‐1a and miRNA‐15b. Combinatorial inhibition of miR‐1a and miR‐15b enhances cardiomyocyte proliferation, improves heart function, and reduces fibrosis in myocardial infarction models.
Ting Yuan, Meiqian Wu, Chaonan Zhu, Hao Yu, Minh Duc Pham, Katharina Bottermann, Yijie Mao, Yue Wang, Mathias Langner, Mirko Peitzsch, Arka Provo Das, Silke Kauferstein, Jonathan Ward, Peter Mirtschink, Andreas Michael Zeiher, Stefanie Dimmeler, Jaya Krishnan   +16 more
wiley   +1 more source

PGMweb: an online tool for visualizing the X-ray beam path through plane grating monochromators. [PDF]

J Synchrotron Radiat
Wang PY, Bazan da Silva M, Hand M, Wang H, Chang P, Beilsten-Edmands V, Kim TK, Lee TL, Sawhney K, Walters AC.   +9 more
europepmc   +1 more source

Uncover Hidden Physical Information of Soft Matter by Observing Large Deformation

Advanced Science, EarlyView.
Detecting internal abnormalities in soft matter remains challenging due to its heterogeneous nature. This study introduces a method that infers hidden physical properties by matching observed deformation with simulation through parallel Bayesian optimization.
Huanyu Yang, Yitao Cheng, Penghui Zhao, Jiageng Cai, Zhaowei Yin, Shaomin Chen, Ge Guo, Chi Zhu, Ke Liu, Lingyun Zu   +9 more
wiley   +1 more source

A python library for the fast and scalable computation of biologically meaningful individual specific networks. [PDF]

Sci Rep
Lalli G, Li Z, Melograna F, Collier J, Moreau Y, Raimondi D, Van Steen K.   +6 more
europepmc   +1 more source

High‐Speed 3D Printing Coupled with Machine Learning to Accelerate Alloy Development for Additive Manufacturing

Advanced Science, EarlyView.
This work shows combining high‐throughput experiments of metal 3D printing with data science‐driven prediction leads to faster alloy development. Researchers develop steel alloy specimens specifically for 3D printing by adjusting aluminum content (0–10 wt.%) and energy input during printing.
Avinash Hariharan, Marc Ackermann, Stephan Koss, Ali Khosravani, Johannes Henrich Schleifenbaum, Patrick Köhnen, Surya R. Kalidindi, Christian Haase   +7 more
wiley   +1 more source

Mitofusin 1 Drives Preimplantation Development by Enhancing Chromatin Incorporation of Histone H3.3

Advanced Science, EarlyView.
MFN1 exerts its function partially through histone H3.3 in early embryos. MFN1 colocalizes with PADI6, and its deficiency results in compromised cytoplasmic lattices and ribosomal subunits, leading to declined H3.3 protein level. This, in turn, hinders the incorporation of H3.3 into the embryonic genome, thereby causing failure of male pronucleus ...
Xiao‐yan Shi, Yu Tian, Yu‐fan Wang, Yi‐ran Zhang, Ying Yin, Qing Tian, Lei Li, Bing‐xin Ma, Ximiao He, Li‐quan Zhou   +9 more
wiley   +1 more source

CRISPR-Hybrid: A CRISPR-Mediated Intracellular Directed Evolution Platform for RNA Aptamers. [PDF]

Nat Commun
Su-Tobon Q, Fan J, Goldstein M, Feeney K, Ren H, Autissier P, Wang P, Huang Y, Mohanty U, Niu J.   +9 more
europepmc   +1 more source

MMP9High Neutrophils are Critical Mediators of Neutrophil Extracellular Traps Formation and Myocardial Ischemia/Reperfusion Injury

Advanced Science, EarlyView.
During a heart attack, neutrophils rapidly activate and differentiate into a specific subset characterized by high levels of MMP9, a tissue‐damaging enzyme, via the SPI1/CST7 pathway. These neutrophils form harmful net‐like structures (Neutrophil extracellular traps, NETs) that exacerbate heart injury.
Shiyu Hu, Feng Zhang, Jingpu Wang, Jian Zhang, Chenguang Li, Yang Lyu, Yiwen Wang, Rong Huang, Yang Gao, Hongbo Yang, Juying Qian, Wenwen Tang, Jiatian Cao, Junbo Ge   +13 more
wiley   +1 more source

SciJava Ops: an improved algorithms framework for Fiji and beyond. [PDF]

Front Bioinform
Selzer GJ, Rueden CT, Hiner MC, Evans EL, Kolb D, Wiedenmann M, Birkhold C, Buchholz TO, Helfrich S, Northan B, Walter A, Schindelin J, Pietzsch T, Saalfeld S, Berthold MR, Eliceiri KW.   +15 more
europepmc   +1 more source