Results 151 to 160 of about 5,534,746 (396)

Onasemnogene Abeparvovec in Type I Spinal Muscular Atrophy: 24‐Month Follow‐Up From the Italian Registry

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Onasemnogene abeparvovec (OA) is an AAV9‐based gene therapy for spinal muscular atrophy type I (SMA I). Real‐world outcomes show increased response variability compared to clinical trials, and follow‐up data beyond 12–18 months are limited.
Marika Pane, Giorgia Coratti, Chiara Cutrì, Antonio Varone, Riccardo Masson, Adele D'Amico, Valeria Sansone, Sonia Messina, Federica Ricci, Chiara Ticci, Claudio Bruno, Caterina Agosto, Francesca Benedetti, Antonella Pini, Sabrina Siliquini, Massimiliano Filosto, Alberto Zambon, Ilaria Bitetti, Maria Rosaria Manna, Claudia Dosi, Riccardo Zanin, Stefano Parravicini, Roberto De Sanctis, Giulia Stanca, Michela Catteruccia, Michele Tosi, Irene Mizzoni, Emilio Albamonte, Valentina Franchino, Maria Sframeli, Ilaria Cavallina, Elena Procopio, Michele Sacchini, Simone Morando, Noemi Brolatti, Federica Trucco, Gaia Scarpini, Elena Briganti, Beatrice Berti, Concetta Palermo, Daniela Leone, Stefano C. Previtali, Eugenio Mercuri, the ITASMAC working group   +43 more
wiley   +1 more source

Belbin Revisited: The Construct Validity of the Interplace II Team Role Instrument

In the present study the construct validity of the revised edition of the Belbin Team Roles measure, the so-called Interplace II program, is tested. Three parallel parts were used to determine someone’s team roles.
Dierendonck, D. van, Groen, R.
core  

A Water Footprint Management Construct in Agri-Food Supply Chains: A Content Validity Analysis [PDF]

, 2022
Marcelo Werneck Barbosa, José Manuel Cansino Muñoz-Repiso   +1 more
openalex   +1 more source

IV Thrombolysis Facilitates Interventional Reperfusion in Non‐Cardioembolic but Not Cardioembolic Stroke

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Intravenous thrombolysis (IVT) before thrombectomy for ischemic stroke may alter clot structure and procedural performance. We investigated how IVT relates to thrombectomy metrics across stroke etiologies. Methods We performed a time‐to‐event analysis of consecutive patients with anterior circulation large vessel occlusion (acLVO ...
Annahita Sedghi, Daniel P. O. Kaiser, Martin Arndt, Norma J. Diel, Erik Simon, Witold H. Polanski, Volker Puetz, Hagen B. Huttner, Timo Siepmann   +8 more
wiley   +1 more source

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

Criterion-related construct validity

construct validity, criterion-related validity, discriminant validity, latent variable models, conditional independence, probability inequalities, item response theory,
Paul Rosenbaum
core   +1 more source

Construct validity hypothesis tests.

, 2018
Construct validity hypothesis tests.
Ann Van Hecke (3741340), Geraldine Barrett (325858), Ilse Delbaere (5117402), Sofie Verhaeghe (5117399), Dimitri Beeckman (5117396), Joline Goossens (207295)   +5 more
core   +1 more source

The Construct Validity of the ICD-11 Severity of Personality Dysfunction Under Scrutiny of Object-Relations Theory [PDF]

, 2021
Amin Nazari, Steven K. Huprich, Azad Hemmati, Farzin Rezaei   +3 more
openalex   +1 more source

GAD65 Antibody ELISA With Extended Reportable Range: Validation and Guidance for Neurological Practice

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To (1) validate GAD65‐ELISA detection and quantification for type 1 diabetes mellitus and autoimmune neurological diagnoses, (2) correlate ELISA results (reference range < 5 IU/mL) with established radioimmunoprecipitation assay (RIA; ≤ 0.02 nmol/L), and (3) define ELISA clinical utility and pitfalls.
Andrew McKeon, Dana Olofson, Diana Anissian, Divyanshu Dubey, Eoin P. Flanagan, Max C. Herman, Sarosh R. Irani, Daniel H. Lachance, Maria A. Willrich, Sean Pittock, John R. Mills, Anastasia Zekeridou   +11 more
wiley   +1 more source

Construct validity and factor structure of a Spanish-language Social Support Questionnaire during early pregnancy

, 2018
Lauren E Friedman,1 Ana Karen Manriquez Prado,2,* Gabriel Fidel Santos Malavé,2,* Juan Carlos Vélez,3 Rodrigo Winston Gillibrand Esquinazi,4 Sixto E Sanchez,5,6 Qiu-Yue Zhong,1 Bizu Gelaye,1 Michelle A Williams1 1Department of Epidemiology,
Gillibrand Esquinazi RW, Gelaye B, Manriquez Prado AK, Friedman LE, Zhong QY, Vélez JC, Santos Malavé GF, Williams MA, Sanchez SE   +8 more
core