Results 41 to 50 of about 3,507,125 (317)
The French National Archives preserve the collections of the central Architecture services from its revolutionary beginning until the middle of the 19th century (“service des Bâtiments civils et Palais nationaux”, Civil buildings and National Palaces ...
Pascal Riviale, Clothilde Roullier
doaj +1 more source
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Construction projects require certification of quality and progress of work and related payments to ensure successful completion. However, several issues related to quality, progress and payment certifications exist in the construction industry.
G. Thilini Weerasuriya +2 more
doaj +1 more source
INVESTIGATION OF DIGGING MACHINES FOR CONSTRUCTION BY THE “DIAPHRAGM WALL” METHOD
Introduction. Construction in Kazakhstan is one of the leading sectors that has a significant impact on the development of a large number of related industries of the Republic of Kazakhstan. No construction is complete without road construction equipment.
A. S. Kadyrov +3 more
doaj +1 more source
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
The paper substantiates that investment in capital construction and improvement of facilities is the foundation of investment and innovation development of the country.
V.O. Osmyatchenko +2 more
doaj +1 more source
Constructive Proofs or Constructive Statements?
A question raised at previous MAP meetings is the following. Is Sergeraert's "Constructive Algebraic Topology" (CAT, in short) really constructive (in the strict logical sense of the word "constructive")? We have not an answer to that question, but we are interested in the following: could have a positive (or negative) answer to the previous ...
openaire +6 more sources
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source

