Results 41 to 50 of about 8,824 (266)

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Industrial site rehabilitation: Design and challenges [PDF]

E3S Web of Conferences
The article is devoted to the design of reclamation works after completion of construction works on the construction/reconstruction of the railway line of the enterprise.
Pestryakov Alexey Nikolaevich, Sbrodova Nadezhda Vasilyevna, Belyusova Elena Vasilyevna   +2 more
doaj   +1 more source

Reconstruction and modernization of industrial parks [PDF]

E3S Web of Conferences, 2019
The construction of the industrial park is organized in accordance with the program management method, which identifies independent startup industrial and construction complexes that determine the order in which preparatory and basic works are carried ...
Graboviy Petr
doaj   +1 more source

The resources vertical aggregation model in the construction and installation works planning

IOP Conference Series: Materials Science and Engineering, 2019
Abstract The exchange of information between the global and local tasks occurs in the aggregated nomenclature, which reduces the bandwidth requirements of inter-layer communication channels. In the horizontal aggregation scheme, a global task is formed on the basis of non-aggregated information of local systems.
R G Nehay, G S Molotkov, A P Grinev
openaire   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Organizational and technological reliability of construction in Iraq

Вестник СибАДИ, 2023
Introduction. The construction of capital construction facilities is a complex organizational and technological task, providing for the execution of a complex of construction and installation works, as well as organizational and technological interaction
Ahmed Abdul Ruda Awda Al-Msari, A. A. Rudenko   +1 more
doaj   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

A typical digital model of the construction process [PDF]

BIO Web of Conferences
Based on the practical experience of developing digital models of technological processes for the production of construction and installation works, a hypothesis about the similarity of digital models of construction processes is formulated. To prove the
Kabanov Vadim
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source