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Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Analysis of the FIDIC arbitration clause in the light of international jurisprudence [PDF]
The aim of the paper is to present the subject matter related to the procedure of resolving disputes arising in connection with implementation of agreements concluded on the basis of contract models published by the international federation FIDIC in 1999
Agnieszka Dąbrowska
doaj +1 more source
Contract Administration for Construction Professionals
Coggins, J., Schwarz, S., Davies, M., and Ma, T. Contract Administration for Construction Professionals. LexisNexis Australia at www.lexis.com.au, 2022.
Timothy O'Leary
doaj +1 more source
Analisis Kontrak Berbasis Kinerja (Kbk) Dan Kontrak Konvensional Studi Kasus: Proyek Pembangunan Jalan Kbk Semarang-bawen Dan Proyek Pembangunan Jalan Tol Semarang-solo [PDF]
Construction sector in Indonesia, especially for road construction projects are progressing very rapidly in recent years. Indonesia is intensively implementing the road construction project, from new road construction, road maintenance and repairs.
Adi, R. Y. (Rudi) +3 more
core
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Factors affecting rework costs in construction [PDF]
Rework adversely impacts the performance of building projects. In this study, data were analyzed from 788 construction incidents in 40 Spanish building projects to determine the influence of project and managerial characteristics on rework costs. Finally,
Casals Casanova, Miquel +3 more
core +2 more sources
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Umowa o roboty budowlane w zamówieniach publicznych
The subject of deliberations undertaken in the following paper is the obligation relationship between the investor (ordering party) and the executor which arises from concluding the construction work contract by those parties after performing proceedings
Marek Potyraj
doaj +1 more source
Revising contract sum: the employer right to set-off payment [PDF]
Until today, dispute concerning payment had long plague the construction industry. Despite, on what was written on contract on agreed contract price, the employer always dissatisfied with contractor's work.
Saad, Hafiz
core
Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source

