Results 51 to 60 of about 26,800,268 (294)

Literature Review on Green Cost Premium Elements of Sustainable Building Construction

International Journal of Technology, 2018
Despite evidence that sustainable construction practice has numerous environmental, economy and societal benefits, many construction practitioners have failed to support sustainable construction practice due to perceive higher initial cost known as ...
Nazirah Mat Russ, Mahanim Hamid, Kho Mei Ye   +2 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Parametric Method and Building Information Modeling-Based Cost Estimation Model for Construction Cost Prediction in Architectural Planning

Applied Sciences, 2022
Economic feasibility and cost analysis in the preliminary planning stage of early-phase construction projects have a significant impact on project management and implementation.
Seung-Won Yang, Seong-Wan Moon, Hangyeol Jang, Seungyeon Choo, Sung-Ah Kim   +4 more
doaj   +1 more source

Immigration and Construction: Analysis of the Impact of Immigration on Construction Project Costs [PDF]

Journal of Management in Engineering, 2010
There are an estimated 11 million illegal immigrants currently residing in the United States. Of this population, research shows that approximately 19% work in the construction industry, comprising around 14% of all construction workforces. The main objectives of this research are to (1) to predict possible effects of immigration and immigration reform
Sabrina K. Golden, Miroslaw J. Skibniewski   +1 more
openaire   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Modelling construction business performance [PDF]

, 2008
Searching academic databases for records on ‘business failure’, ‘business distress’ or ‘bankruptcy’\ud yields a large body of studies on qualitative, empirical, theoretical and simulation aspects.

core  

Safety Cost Analysis for Building in Construction Industry

International Journal for Research in Applied Science and Engineering Technology, 2023
Abstract: The construction industry provides shelter for a variety of societies and for a variety of purposes. A security culture is concerned with ensuring safety and avoiding risks. A questionnaire is used to collect information for this project.
Sudarshan S. Mangave, Amit S. Sajane, Dr. D. B. Desai, S. K. Patil, Vinod R. Nejka   +4 more
openaire   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source