Results 161 to 170 of about 7,088,681 (334)
Asserting the Portuguese Civil Engineering Identity: the Role Played by the École des ponts et chaussées [PDF]
This paper focuses on the Portuguese engineers who returned to Portugal following a training period at École des Ponts et Chaussées, in Paris between 1831 and 1870.
Matos, Ana Cardoso de
core
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
Various definitions provided for use in OUP Dictionary of Building Construction, Surveying and Civil Engineering 2nd Edition (i..e GLEDSON proposed 35 definitions). [PDF]
Barry Gledson +2 more
openalex
Introduction to the construction technology and control points of prestressed carbon plate in bridge reinforcement engineering [PDF]
Zumin Zhou +3 more
openalex +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Requirements engineering for computer integrated environments in construction [PDF]
A Computer Integrated Environment (CIE) is the type of innovative integrated information system that helps to reduce fragmentation and enables the stakeholders to collaborate together in business.
Aouad, GF, Arayici, Y
core +1 more source
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source

