Results 161 to 170 of about 2,280,486 (356)

Integrative miRNOMe profiling reveals the miR‐195‐5p–CHEK1 axis and its impact on luminal breast cancer outcomes

open access: yesMolecular Oncology, EarlyView.
In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková   +14 more
wiley   +1 more source

The effect of water boundary conditions of advance face and lining on the evolution of internal forces in lining [PDF]

open access: yes, 2015
Feng, S.   +5 more
core   +1 more source

Visualisation of semantic architectural information within a game engine environment [PDF]

open access: yes, 2010
Because of the importance of graphics and information within the domain of architecture, engineering and construction (AEC), an appropriate combination of visualisation technology and information management technology is of utter importance in the ...
De Meyer, Ronald   +2 more
core  

Association of high‐dose radioactive iodine therapy with PPM1D‐mutated clonal hematopoiesis in older individuals

open access: yesMolecular Oncology, EarlyView.
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim   +11 more
wiley   +1 more source

Systems engineering studies of lunar base construction [PDF]

open access: yes
Many ingenious concepts have been proposed for lunar base construction, but few systematic studies exist which relate time-consistent lunar base construction technologies and the choice of lunar base approach with the long-term SEI objectives - i.e ...
Morgenthaler, George W.
core   +1 more source

Practical Guide to Engineering and Construction Contracts

open access: yesConstruction Economics and Building, 2010
Book ReviewPractical Guide to Engineering and Construction Contracts Philip Loots and Donald Charrett, CCH Australia Limited, Sydney 2009, 439 pages plus index, ISBN 9781921593529 (hardback) AUD ...
openaire   +6 more sources

Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management

open access: yesMolecular Oncology, EarlyView.
DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez   +5 more
wiley   +1 more source

SASICE: Safety and sustainability in civil engineering

open access: yes, 2011
The performance of the built environment and the construction sector are of major importance in Europe’s long term goals of sustainable development in a changing climate. At the same time, the quality of life of all European citizens needs to be improved
Azevedo, J   +10 more
core  

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