Results 221 to 230 of about 7,088,681 (334)

Overexpression of CDT1 inhibits cell cycle progression at S phase by interacting with the mini‐chromosome maintenance complex and causes DNA damage

FEBS Open Bio, EarlyView.
CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama, Nonoka Takayama, Rina Tanaka, Yuuki Arai, Yohko Yamaguchi, Yuko Nawata, Yutaro Azuma, Shusuke Tada   +7 more
wiley   +1 more source

Project Risk Propagation Modeling Of Engineering, Procurement And Construction

, 2016
Alireza Atin
openalex   +1 more source

Construction management risk and digital technology: lens of civil engineering, industrial engineering and architecture of eco waste water treatment construction

, 2021
Meilani Meilani, Ken Soebandrija
openalex   +1 more source

Homologous expression and purification of human HAX‐1 for structural studies

FEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

FEBS Open Bio, EarlyView.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul, Alan Strunga, Jiri Damborsky, Zbynek Prokop   +3 more
wiley   +1 more source

Multi-source heterogeneous data fusion and intelligent prediction modeling for chemical engineering construction projects based on improved transformer architecture. [PDF]

Sci Rep
Xin D.
europepmc   +1 more source

Distribution of Engineering Properties of Soils used in Highway Construction

Ritiksha Danu, Amit Kumar Sharma, Anoop Bahuguna, Ankit Negi, Ankit Nainwal   +4 more
openalex   +1 more source

ENGINEERING AND CONSULTING IN CONSTRUCTION: CATEGORY AND CONCEPTUAL ASPECTS [PDF]

, 2019
A.V. Havrylov
openalex   +1 more source

Design Method and Construction Technology in Tunnel Engineering under Complex Geological Conditions

, 2023
Siming Tian, Xue Yang, Zhenyan Tian, Shaoshuai Shi, Weidong Guo, Wei Wang, Ruijie Zhao   +6 more
openalex   +2 more sources

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source