In Vitro Modeling of Natural Killer Cell Cytotoxicity to Inform Personalized ALS Therapeutics
ABSTRACT Objective Natural killer (NK) cells might contribute to motor neuron death in amyotrophic lateral sclerosis (ALS) through direct cytotoxicity, a process that could be inhibited with the FDA‐approved JAK/STAT pathway inhibitor, tofacitinib. This study aimed to verify that tofacitinib can suppress NK cell cytotoxicity, investigate if immune cell
Benjamin J. Murdock+8 more
wiley +1 more source
An integrated GIS-pXRF approach assesses ecological and human health risks from heavy metals in county level soils. [PDF]
Liu S+5 more
europepmc +1 more source
Reusing domains for the construction of reverse engineering tools [PDF]
F. Gouveia de Freitas+1 more
openalex +1 more source
Digital Activity Markers in Chronic Inflammatory Demyelinating Polyneuropathy
ABSTRACT Objective To evaluate the utility of smartwatch and smartphone‐based activity metrics for assessing disease severity and quality of life in patients with chronic inflammatory demyelinating polyneuropathy (CIDP). Methods In the electronic monitoring of disease activity in patients with CIDP (EMDA‐CIDP) trial, we performed a prospective ...
Lars Masanneck+15 more
wiley +1 more source
How to improve performance of Chinese BIM-supported civil engineering projects based on the qualitative comparative analysis method. [PDF]
Zuo W, Mei T, Zhong S, Jiang X, Yan N.
europepmc +1 more source
Value Engineering in Government and Private Sector Construction
William Simpkins
openalex +2 more sources
Objective Promoting Resilience in Stress Management (PRISM) is a resilience coaching program designed for adolescents with chronic illness. We aimed to examine the perceived feasibility, acceptability, and appropriateness of PRISM among pediatric rheumatologists treating adolescents with chronic musculoskeletal pain and obtain recommendations for ...
Sabrina Gmuca+9 more
wiley +1 more source
Life cycle cost of communication towers: identification and hierarchical classification of influencing factors. [PDF]
Zhang J, Wang Y, Xu Q, Gao H.
europepmc +1 more source
Engineering a fast online persistent suffix tree construction [PDF]
Srikanta Bedathur, Jayant R. Haritsa
openalex +1 more source