Results 261 to 270 of about 2,280,486 (356)

Inhibition of Glutamine Metabolism Attenuates Tumor Progression Through Remodeling of the Macrophage Immune Microenvironment

Advanced Biology, EarlyView.
The prodrug strategy used in this study offers new promise for cancer metabolism‐based therapies. JHU083, a prodrug that, when cleaved by protease in the tumor microenvironment, yields the glutamine antagonist DON. JHU083 inhibits tumor growth by targeting glutamine‐addicted cancer cells and suppressing glutamine‐dependent M2 macrophages, leading to a ...
Tianhe Li, Sepehr Akhtarkhavari, Sumeng Qi, Jiawei Fan, Tu‐Yung Chang, Yao‐An Shen, JinMing Yang, Barbara S. Slusher, Ie‐Ming Shih, Stephanie Gaillard, Tian‐Li Wang   +10 more
wiley   +1 more source

Study on forecasting method of power engineering cost based on BIM and DynGCN. [PDF]

PLoS One
Zhai H, Ma J.
europepmc   +1 more source

HMGB1 Derived from the Pyroptotic Microenvironment Promotes Macrophage Extracellular Traps in Hirschsprung‐Associated Enterocolitis

Advanced Biology, EarlyView.
HMGB1 derived from the pyroptotic environment in Hirschsprung‐associated enterocolitis mediates the formation of macrophage extracellular traps through TLR4 ‐p38 MAPK/p65 NF‐kB signaling pathways. Macrophage extracellular traps induce increased ROS production and pyroptosis of colonic epithelial cells.
Rui Zhang, Jing Li, Lili Song, Liya Pan, Chengchen Zhang, Zhiyan Zhan, Li Hong   +6 more
wiley   +1 more source

Deconstructing construction wastes: Exploring waste generation causes and their impact on project performances. [PDF]

PLoS One
Aftab U, Aslam M, Ulhaq A, Jaleel F, Malik S, Zahoor H.   +5 more
europepmc   +1 more source

Novel Biologically Active Glass Fiber Functionalized Using Magnesium Phosphate Cement Promotes Bone and Vascular Regeneration

Advanced Biology, EarlyView.
In this study, a new type of bioactive glass fiber ‐based composite magnesium phosphate bone cement is prepared and verified that its mechanical strength and biological properties. In addition, the cement may have played a biologically active role in the Notch and HIF signaling pathways.
Yuzheng Lu, Yanbo Shan, Yingjie Xiong, Jianting Ye, Yanbin Wu, Jipeng Song, Yao Zhang, Wancheng Lin, Haoye Meng, Wenjing Xu, Jiang Peng, Qiang Lu, Lixiang Ding   +12 more
wiley   +1 more source

Exploring the critical waste factors affecting highway construction projects in Pakistan. [PDF]

PLoS One
Aftab U, Jaleel F, Aslam M, Khan Tipu JA.   +3 more
europepmc   +1 more source

Fecal Microbiota Transplantation Modulates Th17/Treg Balance via JAK/STAT Pathway in ARDS Rats

Advanced Biology, EarlyView.
Fecal microbiota transplantation (FMT) alleviates lung and intestinal injury in lipopolysaccharide (LPS)‐induced acute respiratory distress syndrome (ARDS) in rats. This study demonstrates that FMT restores the balance between Th17 and Treg cells, inhibits the JAK/STAT pathway, and modulates cytokine levels, reducing inflammation and lung damage. These
Dongwei Zhang, Biying Dong, Jie Chen, Zhenqiang Zhang, Weitong Zeng, Longxiong Liao, Xia Xiong, Xuejun Qin, Xianming Fan   +8 more
wiley   +1 more source

キョウメイ シンドウホウ ニヨル ツチ ノ ドウテキ ケイスウ ノ ケンキュウ [PDF]

, 1978
Kaku, Ken, Laboratory of Construction Engineering, Faculty of Agriculture, Saga University, Laboratory of Construction Engineering, Faculty of Agriculture, Saga University, Yoshida, Isao, カク, ケン, ヨシダ, イサオ, 加来, 研, 吉田, 勲   +7 more
core  

Nutrient accumulation and fertilizer potential of terrace section soils in loess areas. [PDF]

Sci Rep
Lei N, Zhang J, Zhang J, Sun Z, Wang Z.
europepmc   +1 more source

A CONSIDERATION ON THE EVALUATION OF GEOTECHNICAL RISK INVOLED IN CONSTRUCTION PROJECTS BASED ON FINANCE ENGINEERING THEORY

, 2003
Hiroyasu Ohtsu, Yoshiki ONOI, Yuzo OHNISHI, Kyu Lee   +3 more
openalex   +2 more sources