Results 51 to 60 of about 474,928 (297)

LOGISTICS RISK RESEARCH OF PREFABRICATED HOUSE CONSTRUCTION ENGINEERING BASED ON CREDIBILITY METHOD [PDF]

open access: yesCivil Engineering Journal, 2017
In recent years, the prefabricated house industry has rapid development,.Because of fewer suppliers, higher demand transport scheme and complex quality test, the risks of construction engineering logistics links are relatively high.
Xiaoping Bai, Huifang Zhao
doaj   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Building Information Modeling BIM - Level of Digital Construction

open access: yesArchives of Civil Engineering, 2017
In the paper the topic of Building Information Technology BIM is investigated. It is new in Polish circumstances technology for construction and for building product industry, which contribute to change and develop level of industrialization.
Glema A.
doaj   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

A contribution to the lexis of construction engineering textbooks

open access: yesIbérica, 2008
The integration of a genre-based and a corpus-based instruction in ESP learning (Swales, 1990; Tribble, 2000; Ferguson, 2001; Flowerdew, 2005) has proved to be a suitable theoretical framework for describing the lexis of construction and architecture ...
Concepción Orna Montesinos
doaj  

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Characteristics of Authentic Construction Learning Experiences to Enable Accurate Consideration of Cost-Effective Alternatives

open access: yesBuildings
Authentic learning opportunities that simulate full-scale design and construction using real materials provide valuable experiential learning environments for construction and civil engineering students by challenging students to apply building concepts ...
Karan R. Patil   +6 more
doaj   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Leveraging digital tools to advance mathematics competencies among construction students

open access: yesCogent Education
This study investigated the impact of integrating design-technological activities on developing mathematical competencies among construction engineering students. A mixed methods approach compared curriculum delivery with and without digital tools across
Elmira Saparbayeva   +4 more
doaj   +1 more source

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