Results 61 to 70 of about 2,500,532 (382)

Development of multilayer constructs for tissue engineering [PDF]

open access: yesJournal of Tissue Engineering and Regenerative Medicine, 2012
The rapidly developing field of tissue engineering produces living substitutes that restore, maintain or improve the function of tissues or organs. In contrast to standard therapies, the engineered products become integrated within the patient, affording a potentially permanent and specific cure of the disease, injury or impairment.
N.M.S. Bettahalli   +7 more
openaire   +3 more sources

Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms

open access: yesFEBS Letters, EarlyView.
Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze   +3 more
wiley   +1 more source

Automatic detection method of abnormal vibration of engineering electric drive construction machinery

open access: yesElectronic Research Archive, 2023
Aiming at the problem that the extraction effect of abnormal vibration characteristics of current engineering electric drive construction machinery is poor, an automatic detection method of abnormal vibration of engineering electric drive construction ...
Jian Yuan , Hao Liu, Yang Zhang
doaj   +1 more source

The solution supramolecular structure of α2 → 8 polysialic acid suggests a structural cause for its low immunogenicity

open access: yesFEBS Letters, EarlyView.
α2 → 8 polysialic acid elicits poor immunogenicity. Small‐angle scattering shows a supramolecular structure with parallel‐chain binding, although in different forms at μm and mm calcium. The major histocompatibility complex requires molecular weights around 2000 Da to produce antibodies, and 2000 Da polysialic oligomers will bind in these structures ...
Kenneth A. Rubinson
wiley   +1 more source

Public Perceptions of the Midwest’s Pavements - Wisconsin - Phase I (Winter Ride) [PDF]

open access: yes, 2001
The Wisconsin Winter Ride Survey was designed to determine the extent to which drivers were tolerant of the rougher ride of pavements on rural two-lane highways in the winter.
Marquette University,Department of Civil, Construction, and Environmental Engineering
core   +1 more source

Construction And Research Of Full Balance Energy Of Variational Problem Motion Surface And Groundwater Flows [PDF]

open access: yes, 2017
Based on the laws of conservation of mass and momentum the basic equations of motion with unknown quantities velocity and piezometric pressure are written.
Venherskyi, P. (Petro)
core   +2 more sources

Proceedings Third International Workshop on Engineering Safety and Security Systems [PDF]

open access: yesEPTCS 150, 2014, 2014
The International Workshop on Engineering Safety and Security Systems (ESSS) aims at contributing to the challenge of constructing reliable and secure systems. The workshop covers areas such as formal specification, type checking, model checking, program analysis/transformation, model-based testing and model-driven software construction.
arxiv   +1 more source

Refining the NaV1.7 pharmacophore of a class of venom‐derived peptide inhibitors via a combination of in silico screening and rational engineering

open access: yesFEBS Letters, EarlyView.
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma   +8 more
wiley   +1 more source

A three-dimensional intelligent engineering management and control system for the construction of a long-span valve hall project based on a microservice architecture.

open access: yesPLoS ONE, 2021
Three-dimensional intelligent engineering management and control systems (EMCS) based on the browser/server (B/S) model are an important part of intelligent engineering development.
Qinghe Zeng   +6 more
doaj   +1 more source

Identification of novel small molecule inhibitors of ETS transcription factors

open access: yesFEBS Letters, EarlyView.
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla   +9 more
wiley   +1 more source

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