Results 141 to 150 of about 7,695,805 (356)

A framework for introducing the private finance initiative in Brunei Darussalam construction industry. [PDF]

, 2008
The Private Finance Initiative (PFI) is a common, and sometimes preferred, approach to funding public projects without immediate recourse to the public purse, in the construction industry in developed countries throughout the world.
Mohammad, S.A., Tutesigensi, A.
core  

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Development and Performance Evaluation of a Novel Disc-Buckle Steel Scaffold Joint

Buildings
The disc-buckle scaffold system demonstrates significant advantages in prefabricated construction applications, particularly in terms of installation efficiency, load-bearing capacity, and standardization.
Si Wei, Yu Xu, Bing Yuan, Haofan Chen, Genquan Zhong, Guoyan Zhang   +5 more
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Exploring Perceptions toward Emotional Intelligence in Chilean Construction Using a Qualitative Approach

Buildings
This study aims to analyze the perceptions of construction experts in the Chilean construction industry regarding emotional intelligence. This exploratory and qualitative study is based on data collected through semi-structured interviews with ...
Pedro Páez, Felipe Araya, Luis Arturo Salazar, Zulay Giménez, Omar Sánchez, Leonardo Sierra-Varela, Briguitte Neculman   +6 more
doaj   +1 more source

A Comparative Analysis of Visualization Methods in Architecture: Employing Virtual Reality to Support the Decision-Making Process in the Architecture, Engineering, and Construction Industry

, 2023
Ahmed Redha Gheraba, Debajyoti Pati, Clifford B. Fedler, Marcelo Raul Schmidt, Michael S. Molina, Ali Nejat, Muge Mukaddes Darwish   +6 more
openalex   +1 more source

Are we catering to the construction industry KM requirements?: A literature synthesis [PDF]

The concept of Knowledge Management is now familiar to the construction industry and various attempts are being made for the effective management of knowledge in the industry.
Amaratunga, Dilanthi, Haigh, Richard, Pathirage, C. P.   +2 more
core  

Job costing: An analysis of the construction industry [PDF]

, 2018
The construction industry in New Zealand is very large and shows no signs of slowing down in the near future. It is one of the largest contributors for employment growth.
Bosman, Rudi, Bottomley, Blake
core  

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source