Results 121 to 130 of about 3,082,738 (358)
Molecular Oncology, EarlyView.In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern +7 more
wiley +1 more source
Design and construction aspects of a geocomposite drainage system in a dam [PDF]
, 2012 The drainage system of a dam depends mainly of the available granular material founded near the dam site and it’s quantities. In some cases, the use of natural granular materials can reach an impracticable cost considering the transportation and the ...
Gerheim Souza Dias, Tiago +1 more
core +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Measuring material wastage on construction sites: a case study of local authority highway projects [PDF]
, 2010 The construction industry in the UK is vast. It is one of the largest sectors of the economy with an output of over £100 billion, representing approximately 8% of the country’s GDP.
Swinburne, Jonathan +2 more
core
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
Rice husk ash as an indigenous construction material in building process, a statistical evaluation [PDF]
, 2021 Ndubuisi Micheal Odoanyanwu +2 more
openalex +1 more source
Materials and techniques for model construction [PDF]
The problems confronting the designer of models for cryogenic wind tunnel models are discussed with particular reference to the difficulties in obtaining appropriate data on the mechanical and physical properties of candidate materials and their ...
Wigley, D. A.
core +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
The Application and Effects of Aerogel in Ultra-Lightweight Mineralised Foams
BuildingsThis study aims to explore the potential of aerogel to optimise the thermal conductivity of mineralised foam materials. Experiments were conducted with (i) addition methods of aerogel, (ii) proportion of aerogels in cement slurry, and (iii) water/cement ...
Tongyu Xu +3 more
doaj +1 more source