Results 121 to 130 of about 8,806,849 (303)

Assessment for Sustainable Use of Quarry Fines as Pavement Construction Materials: Part I—Description of Basic Quarry Fine Properties

open access: yes, 2019
As a secondary material, quarry fines are a valuable material to be reused for many purposes in civil engineering projects. The aggregate source depletion, especially the lack of high quality aggregates as expected in the future, as well as the demand ...
Amandine Miksic   +7 more
core   +1 more source

Influence of Enhanced Exterior Insulation on the Mechanical Properties, Durability, and Microstructure of UHPC in Low-Temperature Environments

open access: yesAdvances in Civil Engineering
This study addresses the performance development and microstructural evolution of ultrahigh performance concrete (UHPC) in low-temperature environments (0–5°C) by proposing an external enhanced-insulation curing method.
Jiawen Liu   +6 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Effects of fibre reinforcements on properties of extruded alkali activated earthen building materials

open access: yes, 2019
The reaction between clay minerals present in soil and an alkaline solution has the potential to develop in situ binders, which can be harnessed in the development of earth based construction materials.
Mustapha, Kabiru   +6 more
core   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Author Correction: Multi-layered cement-hydrogel composite with high toughness, low thermal conductivity, and self-healing capability

open access: yesNature Communications, 2023
Yuan Chen   +7 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

CONSTRUCTION MATERIALS

open access: yes
Building construction materials have been used by humans since (at least) the times we stopped being hunters–gatherers and settled down to stay in dwellings. The choice of the materials for building the 'infrastructure' has developed extensively since these times.
  +6 more sources

The Application and Effects of Aerogel in Ultra-Lightweight Mineralised Foams

open access: yesBuildings
This study aims to explore the potential of aerogel to optimise the thermal conductivity of mineralised foam materials. Experiments were conducted with (i) addition methods of aerogel, (ii) proportion of aerogels in cement slurry, and (iii) water/cement ...
Tongyu Xu   +3 more
doaj   +1 more source

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