Results 121 to 130 of about 14,503,149 (250)
Shear behavior and construction method of steel shear keyed joints in precast segmental beams. [PDF]
Sci Rep, 2023 Zou Y, Xiang T, Xu D.
europepmc +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Construction Workers Health Trust activity report.
, 2001 The Construction Workers Health Trust was founded following a decision taken at the Construction 2000 Conference in May 1994 by the Construction Group of Unions affiliated to the Irish Congress of Trade Unions, to establish a body dedicated solely to ...
Construction Workers Health Trust
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Retracted: Construction Method of Industrial College in Vocational Colleges Based on Cluster Analysis Algorithm. [PDF]
Comput Math Methods Med, 2023 Methods In Medicine CAM.
europepmc +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Reduced-Cost Second-Order Algebraic-Diagrammatic Construction Method for Core Excitations. [PDF]
J Chem Theory Comput, 2023 Mester D, Kállay M.
europepmc +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Final report : your building [PDF]
, 2007 The Your Building Project to build a website as the business and technical guide to\ud sustainable commercial buildings has now been completed. The site is available at\ud www.yourbuilding.org.
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Dataset construction method of cross-lingual summarization based on filtering and text augmentation. [PDF]
PeerJ Comput Sci, 2023 Pan H, Xi Y, Wang L, Nan Y, Su Z, Cao R.
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Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source