Results 41 to 50 of about 166,792,772 (228)

Biosensors for Cancer Biomarkers Based on Mesoporous Silica Nanoparticles

open access: yesBiosensors
Mesoporous silica nanoparticles (MSNs) exhibit highly beneficial characteristics for devising efficient biosensors for different analytes. Their unique properties, such as capabilities for stable covalent binding to recognition groups (e.g., antibodies ...
Minja Mladenović   +5 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Finite element solutions to boundary value problems [PDF]

open access: yes, 1976
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.This thesis consists of two distinct parts which deal with two-point boundary value problems and parabolic problems, respectively.
Moore, P
core   +6 more sources

Analysis of water inflow conditions and prediction for water inflow of deep-buried tunnels in the karst area of Southwest China: Taking Dapozi tunnel of central Yunnan Water Diversion Project as an example

open access: yesCarsologica Sinica, 2023
The karst area in Southwest China is characterized by complex terrain and karst development, with a large area of exposed carbonate rocks and a wide distribution of karst depressions and valleys on the surface.
Yiming LUO   +5 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Slope stability and surface displacement analysis of the Kuther Landslide in the Dehar Watershed, Himachal Himalaya, Northern India

open access: yesDiscover Geoscience
The road network in the Himalayan terrain is vital for India's socio-economic development and national security, yet the complexities of topography, geological structures, diverse lithology, and neotectonics make planning and maintaining these routes a ...
Arun Kumar   +5 more
doaj   +1 more source

Application of MODFLOW-CFPv2 model in karst tunnel water inrush and its impact on groundwater environment: Example of the Mengkuanggou karst water system in Heqing County, Yunnan Province

open access: yes地质科技通报
Objective In the central Yunnan region, the geological structure is complex and karst formations are prevalent. Sudden water gushing and attenuation of spring flow are among the most difficult problems in tunnel construction. The Mengkuanggou karst water
Jing XIAO   +6 more
doaj   +1 more source

TERAHERTZ COMMUNICATION SYSTEMS FOR HIGH-DEFINITION AND ULTRA-HIGH-DEFINITION TELEVISION TRANSMISSION

open access: yesInformation and Telecommunication Sciences, 2022
Background. The advent of HD and UHD video formats, and as a result the growing volume of accumulated and transmitted data led to the demand for higher data rate of wireless communications.
Гліб Авдєєнко   +2 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Stable expression of Mycobacterium bovis antigen 85B in auxotrophic M. bovis bacillus Calmette-Guérin

open access: yesMemorias do Instituto Oswaldo Cruz
BACKGROUND Bovine tuberculosis (TB) is a zoonotic disease caused by Mycobacterium bovis, responsible for causing major losses in livestock. A cost effective alternative to control the disease could be herd vaccination. The bacillus Calmette-Guérin (BCG)
Caroline Rizzi   +8 more
doaj   +1 more source

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