Results 141 to 150 of about 4,778,092 (301)

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Constructing Process Models Systematically

open access: yesChemical Engineering Transactions, 2015
Models are the starting point for any computation-based engineering activity and thus errors in the construction - instantiation - coding of models are beyond the most expensive ones. Any improvement of this situation requires a systematic approach that enables automatic generation of coded models.
openaire   +2 more sources

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Process Transparency on Construction Sites: Examples from Construction Companies in Brazil [PDF]

open access: yes
Process transparency is the core concept in Visual Management (VM), which is one of the founding blocks of the Toyota Production System. This paper presents the preliminary results of a collaborative research conducted between Brazil and the UK, as part ...
Alves, Thais   +7 more
core  

IMPROVING SAFTEY PERFORMANCE IN CONSTRUCTION PROJECTS IN LIBYA (CASE STUDY : IN TRIPOLI CITY) [PDF]

open access: yes, 2011
In both developed and developing countries, the construction industry is considered to be one of the most significant industries in terms of its impact on health and safety of the working population.
Agung W, Muhammad   +2 more
core  

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Review of 70 years’ achievements and high-quality development architecture system of surface coal mining in China

open access: yesMeitan xuebao
As an important component of China’s coal industry, surface coal mines have the advantages of large production capacity, low mining costs, and great safety conditions.
Qingxiang CAI, Yanlong CHEN
doaj   +1 more source

THE EFFECTIVENESS OF GAMES AND SONGS IN TEACHING ENGLISH VOCABULARY TO THE FOURTH GRADE STUDENTS OF SDN 1 BATURETNO WONOGIRI [PDF]

open access: yes, 2008
Woro Widiastuti. 2008. The Effectiveness of Games and Songs in Teaching English Vocabulary to the Fourth Grade Students of SDN 1 Baturetno, Wonogiri. English Diploma Program, Faculty of Letters and Fine Arts, Sebelas Maret University.
Widiastuti , Woro
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

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