Results 41 to 50 of about 66,254 (264)

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw   +5 more
wiley   +1 more source

A New Lattice Construction: The Box Product

open access: yesJournal of Algebra, 1999
In a recent paper, the authors have proved that for lattices A and B with zero, the isomorphism $Conc(A \otimes B)\cong Conc A \otimes Conc B$, holds, provided that the tensor product satisfies a very natural condition (of being capped) implying that $A\otimes B$ is a lattice.
Grätzer, George, Wehrung, Friedrich
openaire   +4 more sources

Effects of Add‐On Icosapent Ethyl With Standard Treatment on Functional Outcomes and Inflammatory Biomarkers in Acute Ischemic Stroke: A Blinded Randomized Controlled Trial

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Ischemic stroke, a major cause of mortality and long‐term disability, results from the abrupt cessation of cerebral blood flow due to vascular occlusion or rupture. Icosapent Ethyl (EPA‐EE), approved for hypertriglyceridemia, has anti‐inflammatory and antithrombotic properties that may lessen ischemic damage.
Mitra Mahmoudi Meymand   +5 more
wiley   +1 more source

Design for Manufacturing and Assembly (DfMA) in Construction: A Holistic Review of Current Trends and Future Directions

open access: yesBuildings
The construction industry, despite its anticipated significant growth, has struggled with low productivity over the past two decades. Design for manufacturing and assembly (DfMA), a methodology with a history of success in other industries, presents a ...
Sadaf Montazeri, Zhen Lei, Nicole Odo
doaj   +1 more source

Drivers of Productivity: a Case Study of the Australian Construction Industry

open access: yesConstruction Economics and Building, 2015
Australian construction productivity has grown slowly since 1985 and remains arguably stagnant. The importance of this study is therefore to examine several factors through to be drivers of construction productivity and to understand possible avenues for
Will Chancellor
doaj   +1 more source

A Simplified Laminar Flow Model for the Pultrusion of Glass Fiber/Polyethylene Terephthalate Commingled Yarns

open access: yesAdvanced Engineering Materials, EarlyView.
A simplified thermoplastic pultrusion model is developed to predict thermal fields in glass fiber/polyethylene terephthalate (GF/PET) composites with reduced computational cost. By combining effective material homogenization, validation against literature data, and Gaussian‐process‐based optimization, the study reveals how heating limits, pulling speed,
Elder Soares   +3 more
wiley   +1 more source

Towards improving construction labor productivity and projects’ performance

open access: yesAlexandria Engineering Journal, 2011
Proper management of resources in construction projects can yield substantial savings in time and cost. As construction is a labor-intensive industry, this paper focuses on labor productivity in the construction industry. This study considers the current
Mostafa E. Shehata, Khaled M. El-Gohary
doaj   +1 more source

Estimation of the excavator actual productivity at the construction site using video analysis

open access: yesOrganization, Technology and Management in Construction: An International Journal, 2021
Current estimates of the actual productivity of heavy construction machinery at a construction site are not supported by an appropriate and widely used methodology.
Šopić Martina   +3 more
doaj   +1 more source

Molecular Dynamics Studies of Shape Memory Polymers: From Bead–Spring Models to Atomistic Simulations

open access: yesAdvanced Engineering Materials, EarlyView.
Coarse‐grained (left) and atomistic (right) models of the shape memory polymer ESTANE ETE 75DT3 are shown schematically. The two representations bridge molecular detail and mesoscopic description. Both models capture shape memory behavior, linking segmental mobility and conformational relaxation of anisotropic chains to macroscopic recovery, and ...
Fathollah Varnik
wiley   +1 more source

Additive Manufacturing as an Enabler of Lean Construction: A Systematic Literature Review

open access: yesBuildings
Additive manufacturing (AM) has been increasingly explored in the construction sector for its potential to improve productivity, reduce waste, and enable design flexibility; however, reported outcomes remain inconsistent, and the relationship between AM ...
Hind Jebbouri   +2 more
doaj   +1 more source

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