Results 191 to 200 of about 847,107 (317)

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Early detection of construction project risks in Saudi Arabia: a mixed-methods study on warning signs and mitigation. [PDF]

Sci Rep
Alsulami BT, Al-Shaery AM, Kassem MA.
europepmc   +1 more source

Value Proposition for Enabling Construction Project Innovation by Applying Building Information Modeling.

Comput Intell Neurosci, 2022
Liu H, Ju Q, Zhao N, Li H, Skibniewski MJ.   +4 more
europepmc   +1 more source

United states department of defense (DoD) real property repair, alterations, maintenance, and construction project contract data: 2009-2020. [PDF]

Data Brief, 2020
Stout T, Teston A, Langhals B, Delorit J, Hendrix C, Schuldt S.   +5 more
europepmc   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Examining the Impact of Project Performance on Investment Success within Iran's National Development Fund Financing System

مدیریت بهره وری
Ensuring the timely allocation of necessary financial resources is a critical success factor for achieving optimal predominant project performance and one of the most important factors in the success of the investment.
Shima Yarahmadi, Ehsan allah Eshtehardian, Saeed Taheri, mohammad hossein sobhiyah   +3 more
doaj  

An improved multi-objective animated oat optimization algorithm for resource-constrained construction project organization design. [PDF]

Sci Rep
Xue Q, Wu C, Nie J, Zhou S, Liu H, Katsikis VN.   +5 more
europepmc   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Impact assessment of the ophthalmology discipline construction project at Tianjin Medical University Eye Hospital. [PDF]

Health Res Policy Syst
Sun H, Li X, Yu X, Li F, Zhang T, Song J, Du Y, Liu H.   +7 more
europepmc   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source