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ABSTRACT Objective Intravenous thrombolysis (IVT) before thrombectomy for ischemic stroke may alter clot structure and procedural performance. We investigated how IVT relates to thrombectomy metrics across stroke etiologies. Methods We performed a time‐to‐event analysis of consecutive patients with anterior circulation large vessel occlusion (acLVO ...
Annahita Sedghi +8 more
wiley +1 more source
ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan +9 more
wiley +1 more source
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From Construction Project Success to Integrated Construction Project Selection
Construction Research Congress 2010, 2010It is noted that project success and project selection and their corresponding criteria and factors have been treated as two separate project management topics. Project success and project selection have not been related to each other yet, but according to our research, they share at least fourteen common traits. This paper seeks to identify the common
Morteza Shokri-Ghasabeh +2 more
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This chapter provides a general introduction to the companion, to FIDIC as an organisation and to the FIDIC contractual framework. It also includes a general guide to drafting international contracts as well as a more specific guide to drafting FIDIC based contracts.
Patrick Burgess, Nicholas Foulcher
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Patrick Burgess, Nicholas Foulcher
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Systematizing Construction Project Evaluations
Journal of Management in Engineering, 1996Present trends toward multiparticipant megaprojects have heightened the need for effective and efficient evaluations by stakeholders, both of themselves and of fellow participants. Feedback from such evaluations helps improve the management of ongoing and oncoming projects. It also assists in a more objective selection of suitable organizational and/or
Thorpe, A, Kumaraswamy, MM
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Pragmatism’s Constructive Project
2014Among the many strengths of The Pragmatic Turn are Richard Bernstein’s understanding of and sympathy with a large number of voices within the broad pragmatist tradition, his ability to set those voices in conver- sation with one another, and his keen ear for the moments at which they start to bluster or to mumble or simply to dry up altogether.
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Construction Project Management
Construction Management and Economics, 2013Given the plethora of texts that already exist in construction project management, (many eponymously titled), any author feeling the need to contribute yet another must be motivated by the strong c...
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