Results 121 to 130 of about 17,997,904 (297)

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Under the Clouds of War

, 1972
Consists of film clips of World War II events, including Mussolini\u27s invasion of Ethiopia and Hitler\u27s march into Austria.
Time-Life Video
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Canadian Construction R & D Performers and Funders: A Report Prepared for the Institute for Research in Construction by the Canadian Construction Innovation Council

, 2005
This report on Construction Research and Development Performers and Funders is fifth in the series started in 1983. Previous inventories/surveys were based on activities in 1983, 1987, 1992 and 1998.
Canadian Construction Innovation Council
core   +1 more source

Desvios de custos e prazos em empreendimentos da construção civil: categorização e fatores de influência

Ambiente Construído
Desvios de custos e prazos são desafios recorrentes na construção civil. Neste artigo, os autores objetivaram revisar sistematicamente a literatura relacionada a desvios de prazos e custos para determinar uma estrutura de categorização e respectivos ...
Elisa Atália Daniel Muianga, Ariovaldo Denis Granja, Joyce de Andrade Ruiz   +2 more
doaj   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Forecasting Total and Type-Specific Non-Residential Building Construction Spending: The Case Study of the United States and Lessons Learned

Buildings
Forecasting construction spending is important for civil engineering practitioners to make business decisions. Currently, the main body of forecasting literature pertains exclusively to aggregate construction investment, such as total construction ...
Xingrui Zhang, Yunpeng Wang, Shuai Xu, Eunhwa Yang, Lingxiao Meng   +4 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Final report : your building [PDF]

, 2007
The Your Building Project to build a website as the business and technical guide to\ud sustainable commercial buildings has now been completed. The site is available at\ud www.yourbuilding.org.

core  

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Brite phase 1 report to industry : innovate – now [PDF]

, 2005
Trying to innovate or wanting to? Making a start is the most difficult step on any journey. Whether trying to innovate for the first time, or seeking improvements on current performance, organisations are confronted with a plethora of options. Innovate ―

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