Results 121 to 130 of about 808,049 (434)
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani+14 more
wiley +1 more source
Patterns and determinants of stress among consultant physicians working in Saudi Arabia
Fahad D Alosaimi,1 Hossam S Alawad,2 Ayedh K Alamri,2 Abdullah I Saeed,2 Khalid A Aljuaydi,2 Alwaleed S Alotaibi,2 Khalid M Alotaibi,2 Eiad A Alfaris3 1Department of Psychiatry, College of Medicine, King Saud University, Riyadh, Kingdom of Saudi Arabia ...
Alosaimi FD+7 more
doaj
Between exploitation and control – Clients’ conceptions of the consultant-client relationship [PDF]
During the past years, the use of management consultants has increased significantly, giving managers repeated experiences of both hiring and working with them.
Pemer, Frida, Werr, Andreas
core
Targeted protein degradation in oncology: novel therapeutic opportunity for solid tumours?
Current anticancer therapies are limited by the occurrence of resistance and undruggability of most proteins. Targeted protein degraders are novel, promising agents that trigger the selective degradation of previously undruggable proteins through the recruitment of the ubiquitin–proteasome machinery. Their mechanism of action raises exciting challenges,
Noé Herbel, Sophie Postel‐Vinay
wiley +1 more source
Choosing a consultant in a dynamic investment problem [PDF]
Consider a dynamic decision-making scenario where at every stage the investor has to choose between investing in one of two projects or gathering more information. At each stage, the investor may seek counsel from one of several consultants, who, for a fixed cost, provide partial information about the realized state. We explore the optimal strategy and
arxiv
Target Markets for Grain and Cotton Marketing Consultants and Market Information Systems [PDF]
This paper examines the use of market consultants and market information systems by grain and cotton producers. A model of producer demand for marketing information and consultants is proposed that decomposes price received into exogenous and endogenous ...
Baquet, Alan E.+5 more
core +1 more source
Defining Educational Adequacy [PDF]
In his 2001 ruling of the Lake View case, Judge Kilgore ordered, “an adequacy study is necessary and must be conducted forthwith.” In November 2002, the Arkansas Supreme Court upheld the lower court ruling and mandated that the General Assembly begin an “
McKenzie, Sarah C., Ritter, Gary W.
core +2 more sources
Picking Winners? Investment Consultants' Recommendations of Fund Managers
Investment consultants advise institutional investors on their choice of fund manager. Focusing on U.S. actively managed equity funds, we analyze the factors that drive consultants’ recommendations, what impact these recommendations have on flows, and ...
T. Jenkinson+2 more
semanticscholar +1 more source