Results 151 to 160 of about 691,577 (343)

Enhanced In Situ Bioremediation in Source Zones

open access: yesRevista Águas Subterrâneas, 2011
In situ bioremediation (ISB) can be a low-cost approach for accelerating remediation timelines at sites impacted with dense non-aqueous phase liquids (DNAPLs) such as trichloroethene (TCE) and tetrachloroethene (PCE).
Michaye McMaster   +4 more
doaj  

A systematic review on the birth prevalence of metachromatic leukodystrophy

open access: yesOrphanet Journal of Rare Diseases
Background Metachromatic leukodystrophy (MLD) is an autosomal recessive lysosomal storage disease caused by deficiency in arylsulfatase A (ASA) activity arising primarily from ASA gene (ARSA) variants. Late-infantile, juvenile and adult clinical subtypes
Shun-Chiao Chang   +4 more
doaj   +1 more source

Persistent Leukoencephalopathy Following H1N1 Infection Associated With a Novel MYRF Variant (p.Gly735Asp)

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Mutations in myelin regulatory factor (MYRF) are linked to demyelinating disorders. We report a 38‐year‐old male who developed acute symmetric leukoencephalopathy mimicking a stroke following an influenza A virus infection. While clinical symptoms markedly improved with corticosteroids, MRI revealed persistent white matter lesions, contrasting
Jinghan Hu   +5 more
wiley   +1 more source

Fluid and Neuroimaging Biomarkers in Microgliopathy Colony‐Stimulating Factor‐1 Receptor‐Related Disorders

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aims to identify both fluid and neuroimaging biomarkers for CSF1R‐RD that can inform the optimal timing of treatment administration to maximize therapeutic benefit, while also providing sensitive quantitative measurements to monitor disease progression.
Tomasz Chmiela   +13 more
wiley   +1 more source

Inhibition of Classical and Alternative Complement Pathway by Ravulizumab and Eculizumab

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the feasibility of classical (CH50) and alternative (AH50) complement pathway activity as potential biomarkers for treatment guidance and monitoring during therapy with ravulizumab in patients with generalized myasthenia gravis (gMG) and compare these to therapeutic drug monitoring under eculizumab.
Lea Gerischer   +14 more
wiley   +1 more source

Exploratory Analysis of ELP1 Expression in Whole Blood From Patients With Familial Dysautonomia

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Familial dysautonomia (FD) is a hereditary neurodevelopmental disorder caused by aberrant splicing of the ELP1 gene, leading to a tissue‐specific reduction in ELP1 protein expression. Preclinical models indicate that increasing ELP1 levels can mitigate disease manifestations.
Alejandra González‐Duarte   +13 more
wiley   +1 more source

Generating meaningful and easy-to-interpret sustainability data to support decision making: a method and a case study

open access: yesRevista Águas Subterrâneas, 2013
Recently many corporations, organizations, and governmental agencies are putting a greater emphasis on evaluating sustainability of projects and products to help guide implementation and production.
Matt Vanderkooy   +3 more
doaj  

Between exploitation and control – Clients’ conceptions of the consultant-client relationship [PDF]

open access: yes
During the past years, the use of management consultants has increased significantly, giving managers repeated experiences of both hiring and working with them.
Pemer, Frida, Werr, Andreas
core  

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