Results 71 to 80 of about 835,238 (391)

Strategic Consulting in the Region

open access: yesУправленческое консультирование, 2019
The article is devoted to the procedures of organizing group work in the process of forming the main content of the development strategy of the modern Russian region in accordance with the current legislation, which, however, does not have ...
Yu. N. Lapygin   +2 more
doaj   +1 more source

Raphin‐1 mediates the survival and sensitivity to radiation of pediatric‐type diffuse high‐grade glioma via phosphorylated eukaryotic initiation factor 2α‐dependent and ‐independent processes

open access: yesMolecular Oncology, EarlyView.
Raphin‐1 reduces the survival of PED‐DHGG cells and enhances their radiation sensitivity through both PeIF2α‐dependent and PeIF2α‐independent mechanisms. Raphin‐1 sustains elevated levels of PeIF2α, contributing to its PeIF2α‐dependent effects. Additionally, raphin‐1 interacts with CReP to mediate a separate radiosensitizing pathway that operates ...
Karin Eytan   +4 more
wiley   +1 more source

A Real-World Assessment of Clinical Outcomes and Safety of Eravacycline: A Novel Fluorocycline

open access: yesInfectious Diseases and Therapy, 2020
Background Eravacycline is a novel fluorocycline approved for treatment of intraabdominal infections, with a broad spectrum of activity against a range of pathogens including multidrug-resistant species, including ESBL- or KPC-producing isolates.
Nicholas Van Hise   +11 more
doaj   +1 more source

Memorandum on Preventing Needless Strikes, 1978 [PDF]

open access: yes, 1978
A memo sent to all consultants about how to prevent strikes, September 15 ...
Ogden, Warren C
core   +1 more source

Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation

open access: yesMolecular Oncology, EarlyView.
Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides   +13 more
wiley   +1 more source

Treatment of Acute Osteomyelitis with Once-Weekly Oritavancin: A Two-Year, Multicenter, Retrospective Study

open access: yesDrugs - Real World Outcomes, 2020
Background Acute osteomyelitis is typically caused by Gram-positive pathogens, commonly antibiotic-resistant Staphylococcus species. Standard antibiotic treatment is challenging due to required multiple daily doses, therapeutic drug monitoring, and ...
Nicholas W. Van Hise   +7 more
doaj   +1 more source

From A Service-Learning to A Social-Change Model [PDF]

open access: yes, 2019
Tutor education courses that prepare students to serve as peer writing consultants often include service learning; a typical servicelearning tutor education course involves sending students to tutor in local schools, usually in underserved ...
Savini, Catherine
core   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

Patterns and determinants of stress among consultant physicians working in Saudi Arabia

open access: yesAdvances in Medical Education and Practice, 2018
Fahad D Alosaimi,1 Hossam S Alawad,2 Ayedh K Alamri,2 Abdullah I Saeed,2 Khalid A Aljuaydi,2 Alwaleed S Alotaibi,2 Khalid M Alotaibi,2 Eiad A Alfaris3 1Department of Psychiatry, College of Medicine, King Saud University, Riyadh, Kingdom of Saudi Arabia ...
Alosaimi FD   +7 more
doaj  

A novel approach to in-depth façade assessments: Improved corrosion test methods for embedded steel framing in historic masonry clad buildings [PDF]

open access: yesMATEC Web of Conferences, 2019
Corrosion of structural steel frames and associated steel assemblies within ‘vintage’ buildings circa 1880s to 1930s pose a health and safety risk to the public in major urban centers.
Crevello Gina   +2 more
doaj   +1 more source

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