Results 61 to 70 of about 1,416,682 (312)
ABSTRACT Background Blinatumomab is a bispecific T‐cell engager approved for the treatment of pediatric B‐cell acute lymphoblastic leukemia (B‐ALL). Outpatient home infusion reduces hospitalization burden and optimizes resource utilization, but is logistically challenging.
Angela Parra del Riego +10 more
wiley +1 more source
METHODOLOGICAL APPROACH TO MANAGEMENT CONSULTING DEVELOPMENT
Various management consulting methods are analyzed. Assembling them to the system is offered. The considered methods are classified according to the consulting stages.
Nadezhda A. Serebryakova
doaj
Introducing Academic Advising at Orientation
The First-Year Testing, Consulting, and Advising Program at Penn State introduces students to academic advising and the university's academic structure.
Janet Schulenberg, Cynthia Biek
doaj +1 more source
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
The results of the scientific, medical, organizational and methodological approaches, training of the “Prevention of Infectious Diseases” Research Institute for childhood infections aimed at achieving the main goal - raising children immunized and the ...
S. M. Kharit, T. V. Chernyaeva
doaj +1 more source
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Differences a Day Can Make: Exploring the Effects of Abbreviated Intervention on Improving Financial Management for Youth-serving Organizations [PDF]
This report by the management consulting firm CFAR examines the effectiveness of a one-day workshop and series of webinars offered to nonprofits by the consulting firm FMA as part of a Wallace Foundation initiative to strengthen the financial management ...
core
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source

