Results 51 to 60 of about 84,288 (253)

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

open access: yesFEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes   +32 more
wiley   +1 more source

Identifying and ranking the driving forces of social insurance by analytical hierarchy process: evidence from India

open access: yesHeliyon, 2019
Imperfections in the private market increase the scope of social insurance worldwide. Social insurance is designed to provide protection against heterogeneous risks.
Zahin Ansari   +4 more
doaj   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

open access: yesFEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu   +10 more
wiley   +1 more source

A THEORY OF CONSUMER’S PERCEIVED RISK UNDER THE HALO EFFECT [PDF]

open access: yesManagement & Marketing, 2015
Despite being largely tackled by a manifold of sciences, perceived risk is still a rather unclear concept concerning its formation and update. In today’s economy, where poor purchase decisions are so easy to make, consumers have developed mental shields ...
Dorian-Laurenţiu FLOREA
doaj  

Economic Determination of Modified Multiple Dependent State Sampling Plan under Some Lifetime Distributions

open access: yesJournal of Mathematics, 2021
In this paper, the modification of multiple dependent state sampling plan is proposed and designed for assuring a mean lifetime of the products under Birnbaum–Saunders distribution and Weibull distribution. The optimal parameters of the proposed plan are
Muhammad Aslam   +4 more
doaj   +1 more source

Representative Consumer's Risk Aversion and Efficient Risk-Sharing Rules [PDF]

open access: yes
We study the representative consumer's risk attitude and efficient risk-sharing rules in a singleperiod, single-good economy in which consumers have homogeneous probabilistic beliefs but heterogeneous risk attitudes.
Hara, Chiaki   +2 more
core   +3 more sources

Payday Loans and Deposit Advance Products: A White Paper of Initial Data Findings [PDF]

open access: yes, 2013
During the past year, the Consumer Financial Protection Bureau (CFPB) has engaged in an indepth review of short-term small dollar loans, specifically payday loans extended by nondepository institutions and deposit advance products offered by a small, but

core  

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Investigating the Effect of Risk, Value, and Price Consciousness on Willingness to Purchase Gray Market Goods in Kerman Province

open access: yesتحقیقات بازار یابی نوین, 2011
In the scope of international marketing, gray market has attracted too much attention in recent years. On this basis, the following study examines the factors influencing consumer willingness to purchase gray market goods in Kerman Province.
Ali MollaHosseini, Bahram Jabbarzadeh
doaj   +2 more sources

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