Results 31 to 40 of about 222,550 (277)

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

FEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López, Özge Yilmaz Ardicli, Mübeccel Akdis   +2 more
wiley   +1 more source

THE PRESENT EPIDEMIOLOGICAL CHARACTERISTICS OF YERSINIOSIS IN THE RUSSIAN FEDERATION

Инфекция и иммунитет, 2018
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E. A. Voskresenskaya, G. I. Kokorina, E. B. Ezhlova, Yu. V. Demina, N. D. Pakskina, O. N. Skudareva   +5 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Questions of Immunization in Preparation for the XXII Olympic Winter Games and XI Paralympic Winter Games of 2014 in Sochi

Эпидемиология и вакцинопрофилактика, 2015
The data for the immunization of the population of Sochi resort and the staff during preparation for the XXII Olympic Winter Games and XI Paralympic Winter Games of 2014 in Sochi are presented.
G. G. Onishhenko, A. Ju. Popova, I. V. Bragina, E. B. Ezhlova, Ju. V. Demina, A. A. Mel’Nikova, N. V. Frolova, N. D. Pakskina, V. P. Klinduhov, T. V. Grechanaja, P. N. Nikolaevich, M. I. Balaeva, S. Ch. Tesheva, V. V. Parhomenko, A. N. Kulichenko, D. G. Ponomarenko, G. M. Grizhebovsky, T. V. Taran, D. V. Efremenko, A. D. Antonenko   +19 more
doaj   +1 more source

Genetic diversity of the mumps viruses (Paramyxoviridae: Orthorubulavirus: Mumps orthorubulavirus): an overview

Вопросы вирусологии, 2022
Mumps is an infectious disease controlled by specific vaccine prophylaxis. To date, its social and epidemiological significance remains high. This is evidenced by the process of developing and implementing into the health care practices of many countries
T. S. Chekhlyaeva, D. V. Erokhov, I. Yu. Andrievskaya, P. E. Zherdeva, N. T. Tikhonova   +4 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Anthelmintic resistance against benzimidazoles and macrocyclic lactones in strongyle populations on cattle farms in northern Germany

Scientific Reports
Anthelmintic resistance (AR) in cattle gastrointestinal nematodes (GIN) is an increasing global concern, with low to moderate levels recently documented in Central Europe.
Paula Ehnert, Jürgen Krücken, Stefan Fiedler, Fabian Horn, Christina S. Helm, Ann Neubert, Wiebke Weiher, Werner Terhalle, Stephan Steuber, Ricarda Daher, Georg von Samson-Himmelstjerna   +10 more
doaj   +1 more source

RADIATION CONDITIONS IN KALUGA REGION 30 YEARS AFTER CHERNOBYL NPP ACCIDENT

Радиационная гигиена, 2016
The article describes radiation conditions in the Kaluga region 30 years after the Chernobyl NPP accident. The Chernobyl NPP accident caused radioactive contamination of nine Kaluga region territories: Duminichsky, Zhizdrinsky, Kuibyshevsky, Kirovsky ...
A. G. Ashitko, D. V. Zolochevskiy, O. V. Ovsyannikova, S. A. Rozhkova   +3 more
doaj   +1 more source