Results 31 to 40 of about 1,353,655 (288)

VALUASI EKONOMI MENGGUNAKAN METODE TRAVEL COST PADA TAMAN WISATA ALAM PUNTI KAYU PALEMBANG

Jurnal Ekonomi Pembangunan, 2011
The aim of these study are to estimate the demand similarity of recreation benefit in Taman Wisata Alam Punti Kayu based on travel cost method. The similarity estimate model of recreation demand based on travel cost method that is : Y = 118,323 – 1,419 (
Muhammad Subardin
doaj   +1 more source

Government Subsidy Strategies for Biosimilars R&D Based on Dynamic Game Theory

IEEE Access, 2020
In order to develop the biomedical industry, government subsidy of biosimilars is an incentive policy which has been used by the government. Different government subsidy strategies have an impact on drug price, consumer surplus, social welfare, the ...
Yu Chen, Yipeng Lan, Zhe Huang
doaj   +1 more source

Effects of Maize Importation on the Economic Welfare of Maize Producers and Consumers in Kenya: A Partial Equilibrium Model Approach

Contemporary Agriculture, 2022
Maize imports bridge the maize supply-demand gap in Kenya. However, this does not automatically imply any positive or negative effects of such imports on the economic welfare of maize producers and consumers in the country.
Abodi Maurine Adhiambo, Obare Gideon Aiko, Kariuki Isaac Maina   +2 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

The impact of commercial open source software on proprietary software producers and social welfare

Journal of Industrial Engineering and Management, 2014
Purpose: A growing number of commercial open source software, based on free open source software, appears in many segments of software market. The purpose of this study is to investigate how commercial open source software affects proprietary software ...
Mingqing Xing
doaj   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Emission-reduction investment strategies in competitive shipping supply chains under carbon cap-and-trade mechanisms

Frontiers in Marine Science
Market-based carbon cap-and-trade mechanisms play a pivotal role in reducing the carbon emissions of shipping logistics companies. Focusing on the issue of emission reduction investment in the competitive shipping logistics service supply chain (SLSSCs ...
Guangsheng Zhang, Zhaomin Zhang, Hao Yuan, Weijie Chen   +3 more
doaj   +1 more source

Competitive Price-Quality Strategy of Platforms under User Privacy Concerns

Journal of Theoretical and Applied Electronic Commerce Research, 2022
The behavior-based discrimination price model (BBPD) needs to collect a large amount of user information, which would spark user privacy concerns. However, the literature on BBPD typically overlooks consumer privacy concerns.
Xudong Lin, Xiaoli Huang, Shuilin Liu, Yulin Li, Hanyang Luo, Sumin Yu   +5 more
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source