Results 91 to 100 of about 2,186,983 (292)

Innovations and risk in entrepreneurship

open access: yesПутеводитель предпринимателя, 2020
In article theoretical aspects of business activity in the innovative environment in which the risk and uncertainty are inherent are considered.
Y. V. Sakharnov
doaj  

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Less favoured area measure in the Netherlands: a welcome or negligible addition?

open access: yesApstract: Applied Studies in Agribusiness and Commerce, 2009
The Less Favoured Areas (LFAs) Directive (75/268) which was introduced in 1975, was the first common European instrument of regional agricultural structural policy. LFAs are areas where agriculture is hampered by permanent natural handicaps.
Marleen Schouten   +2 more
doaj   +1 more source

Do Organic Consumers Oppose Genetically Modified Food Stronger than Others? Results of a Consumer Research in Germany [PDF]

open access: yes, 2007
The majority of consumers, in particular European consumers oppose genetic modifi-cation of food. Although consumers oppose strongly genetic modification of food, genetically modified food production increases world wide.
Wirthgen, Antje
core  

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

Do Payday Lending Bans Harm Consumers? Evidence from the Pawn Market [PDF]

open access: yes, 2017
Payday lending is a highly controversial form of short-term, small-dollar credit that is banned in 13 states. Proponents of payday lending claim it provides a needed service to low-income families, and that bans take away options for these consumers ...
Russell, Karlyn
core   +1 more source

Consumable Bodies, Consumable Self

open access: yesExchanges: The Interdisciplinary Research Journal, 2022
‘Nerd’ is everywhere a lonely status, but queer identities and nonconforming gender expressions are especially socially isolating. This article examines the intersection of these two lonely identities, ‘nerd’ and ‘queer’, in Kio Shimoku’s manga Genshiken. Genshiken is a sort of roman-fleuve about a university otaku circle.
openaire   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Data Disparity: Tiered Pricing as an Alternative to Consumer IoT Data Privacy Regulations [PDF]

open access: yes, 2019
In recent years, Internet of Things (IoT) devices have exploded on the consumer scene. These emerging products bring new technological capabilities into our everyday lives. IoT is projected to contribute anywhere from $4-11 trillion to the global economy
LoStocco, Matthew
core   +2 more sources

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

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