Results 121 to 130 of about 2,186,983 (292)
FEBS Open Bio, EarlyView.Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava +3 more
wiley +1 more source
A Risk Management Process for Consumers [PDF]
, 2010 Simply by using information technology, consumers expose themselves to considerable security risks. Because no technical or legal solutions are readily available, the only remedy is to develop a risk management process for consumers, similar to the ...
Cleeff, André van
core +2 more sources
FEBS Open Bio, EarlyView.We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies +3 more
wiley +1 more source
Разработка и регистрация лекарственных средств, 2019 The possibility of applying sedimentation, centrifuge, and filtration techniques for concentration of F. tularensis 15 NIIEG suspensions obtained after submerged cultivation has been evaluated.
D. N. Bibikov +5 more
doaj
Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications
FEBS Open Bio, EarlyView.This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley +1 more source
Exploring origin of food as a source of meanings for Finnish consumers: A qualitative comparison of meanings in Swedish, German and French food [PDF]
, 2004 The findings show that Finnish consumers attach partly overlapping partly distinct cognitive, affective, and normative meanings to Swedish, German, and French food. Swedish and French foods are perceived healthier than German food. Finnish consumers also
Luomala, Harri
core
FEBS Open Bio, EarlyView.Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source
Coproducing a Cochrane Qualitative Evidence Synthesis: Process, Outcomes, and Reflections on Power
Cochrane Evidence Synthesis and MethodsReflecting a broader movement toward knowledge democratization, coproducing Cochrane evidence with interest holders outside universities is increasingly encouraged.
Bronwen Merner, Rebecca Ryan
doaj +1 more source
FEBS Open Bio, EarlyView.This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc +8 more
wiley +1 more source