Results 61 to 70 of about 2,186,983 (292)
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
Биопрепараты: Профилактика, диагностика, лечение, 2018 The present article describes the scientific and methodological development of biotechnological manufacture of test-system components (diagnostic preparations) for instant diagnosis of plague, brucellosis, tularemia, anthrax, cholera.
I. S. Tyumentseva +6 more
doaj
Wearing the arm (or not). Reconceptualising notions of in- and exclusion in Disability Studies
Scandinavian Journal of Disability Research, 2012 In the last few years the social model in Disability Studies has been criticized for focussing too much on social and environmental factors in mechanisms of in- and exclusion and overlooking the materiality and embodied experience of disability.
Maartje Hoogsteyns, Hilje van der Horst
doaj +1 more source
Flexibility, Dissonance and the conscious consumer [PDF]
, 2007 This paper considers the ethical purchasing of what are described as conscious consumers. Conscious consumers present a complex mix of behaviors; while seeking ethical alternatives, other social and economic forces impact on their behavior such that ...
Carrigan, Marylyn +2 more
core
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
Molecular Oncology, EarlyView.In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern +7 more
wiley +1 more source
Инфекция и иммунитетCoinfection is one of the most complex public health issues and is challenging both in choosing treatment strategy and in implementing epidemiological surveillance.
Elena A. Bazykina +3 more
doaj +1 more source
Molecular Oncology, EarlyView.This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert +13 more
wiley +1 more source